{"entity":{"id":"carthera","kind":"company","name":"Carthera","aka":[],"tldr":"Carthera is a French company whose SonoCloud implant, fitted in the skull after brain tumour surgery, sends ultrasound pulses that briefly open the blood-brain barrier before each chemotherapy dose.","summary":"Carthera, founded in 2010 from work at the Pitié-Salpêtrière hospital in Paris, developed the SonoCloud-1 and the larger nine-emitter SonoCloud-9, unfocused ultrasound implants placed in the bone window after tumour resection and activated with intravenous microbubbles to open the blood-brain barrier over a wide region. It has run trials in recurrent glioblastoma with carboplatin and in brain metastases, and is preparing pivotal studies.","asOf":"2026-09-17","links":[{"label":"Official website","url":"https://carthera.eu/"}],"tags":["machines-wave2"],"related":[],"cancers":["glioblastoma","brain-metastases"],"sections":[],"technologies":["transcranial-focused-ultrasound-systems","bbb-focused-ultrasound"],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"hq":"Lyon","country":"FR","companyType":"devices","website":"https://carthera.eu/","founded":2010,"stage":"startup","investors":[],"funding":[]},"route":"/companies/carthera/","neighbours":{"cancer":[{"id":"glioblastoma","kind":"cancer","name":"Glioma & glioblastoma","route":"/cancers/glioblastoma/"}],"term":[{"id":"brain-metastases","kind":"term","name":"Brain metastases (intracranial disease)","route":"/terms/brain-metastases/"}],"technology":[{"id":"bbb-focused-ultrasound","kind":"technology","name":"Focused-ultrasound blood-brain barrier opening","route":"/technologies/bbb-focused-ultrasound/"},{"id":"transcranial-focused-ultrasound-systems","kind":"technology","name":"Transcranial focused ultrasound systems (Exablate Neuro, SonoCloud)","route":"/technologies/transcranial-focused-ultrasound-systems/"}]}}