{"entity":{"id":"cecolin","kind":"drug","name":"Cecolin (bivalent HPV vaccine, Xiamen Innovax)","aka":[],"tldr":"A bivalent HPV vaccine made in China by Xiamen Innovax, prequalified by WHO in October 2021, the earlier of the two Chinese HPV vaccines on WHO's list.","summary":"WHO's list of prequalified vaccines carries Cecolin (Xiamen Innovax Biotech Co. Ltd., regulated by China's National Medical Products Administration) as a bivalent human papillomavirus vaccine in a single-dose vial, prequalified on 14 October 2021. A nine-valent successor, Cecolin 9, was authorised in China in May 2025 (see that record).","status":"approved","asOf":"2026-11-04","links":[{"label":"WHO list of prequalified vaccines (CSV export)","url":"https://extranet.who.int/prequal/vaccines/prequalified/export?page&_format=csv"}],"tags":["preventive-vaccine","hpv-vaccine"],"related":["cecolin-9","walrinvax","hpv-bivalent-vaccine","cervavac","who-prequalified-vaccines"],"cancers":[],"sections":["prevention"],"technologies":["hpv-vaccine"],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":["oncogenic-viruses"],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"brand":"Cecolin","modality":"Prophylactic vaccine (virus-like particles)","mechanism":"Recombinant HPV L1 capsid proteins form virus-like particles that train the immune system to make antibodies against the HPV types the vaccine covers.","approvals":[{"region":"WHO","year":2021,"indication":"WHO prequalification, bivalent HPV vaccine"}],"mechanismSteps":[],"toxicity":[],"access":[],"regulatoryEvents":[{"date":"2021-10-14","type":"approval","region":"WHO","note":"WHO prequalification (WHO list of prequalified vaccines)","source":"https://extranet.who.int/prequal/vaccines/prequalified/export?page&_format=csv"}]},"route":"/drugs/cecolin/","neighbours":{"drug":[{"id":"cecolin-9","kind":"drug","name":"Cecolin 9 (nine-valent HPV vaccine made in E. coli)","route":"/drugs/cecolin-9/"},{"id":"cervavac","kind":"drug","name":"CERVAVAC (quadrivalent HPV vaccine, India)","route":"/drugs/cervavac/"},{"id":"hpv-bivalent-vaccine","kind":"drug","name":"HPV bivalent vaccine (types 16 and 18)","route":"/drugs/hpv-bivalent-vaccine/"},{"id":"walrinvax","kind":"drug","name":"Walrinvax (bivalent HPV vaccine, Yuxi Zerun)","route":"/drugs/walrinvax/"}],"collection":[{"id":"who-prequalified-vaccines","kind":"collection","name":"WHO list of prequalified vaccines","route":"/collections/who-prequalified-vaccines/"}],"section":[{"id":"prevention","kind":"section","name":"Prevention & Risk","route":"/fronts/prevention/"}],"technology":[{"id":"hpv-vaccine","kind":"technology","name":"HPV & HBV vaccination","route":"/technologies/hpv-vaccine/"}],"pathway":[{"id":"oncogenic-viruses","kind":"pathway","name":"Oncogenic viruses","route":"/pathways/oncogenic-viruses/"}]}}