{"entity":{"id":"choi-criteria","kind":"term","name":"Choi criteria (GIST response on CT)","aka":["Choi criteria","Choi response criteria"],"tldr":"The Choi criteria judge whether a gastrointestinal stromal tumour is responding to imatinib by small falls in size or in density on CT, because these tumours often stop growing and go quiet without shrinking much.","summary":"RECIST is insensitive in GIST treated with imatinib. Choi and colleagues (Journal of Clinical Oncology 2007) compared CT with FDG PET in 40 patients: a fall in tumour size of more than 10% or in tumour density of more than 15% on CT identified PET responders with 97% sensitivity and 100% specificity, against 52% and 100% for RECIST. Good responders on CT at two months had a longer time to progression.","asOf":"2026-11-04","links":[{"label":"Choi et al., Correlation of CT and PET in patients with metastatic GIST treated at a single institution with imatinib mesylate: proposal of new CT response criteria (J Clin Oncol 2007)","url":"https://doi.org/10.1200/jco.2006.07.3049"}],"tags":[],"related":["recist","percist"],"cancers":["gist"],"sections":[],"technologies":["ct","fdg-pet"],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"category":"Endpoints"},"route":"/terms/choi-criteria/","neighbours":{"term":[{"id":"percist","kind":"term","name":"PERCIST (PET response criteria in solid tumours)","route":"/terms/percist/"},{"id":"recist","kind":"term","name":"RECIST","route":"/terms/recist/"}],"cancer":[{"id":"gist","kind":"cancer","name":"Gastrointestinal stromal tumour (GIST)","route":"/cancers/gist/"}],"technology":[{"id":"ct","kind":"technology","name":"CT (computed tomography)","route":"/technologies/ct/"},{"id":"fdg-pet","kind":"technology","name":"FDG PET","route":"/technologies/fdg-pet/"}]}}