{"entity":{"id":"clearnote-multi-cancer-epigenomics","kind":"trial","name":"ClearNote Health multi-cancer epigenomics study","aka":[],"tldr":"ClearNote Health's long-running study collecting blood from people with cancer to build its multi-cancer detection test.","summary":"ClearNote Health multi-cancer epigenomics study (NCT03869814) is an observational study sponsored by ClearNote Health. It aims to employ genomic, epigenomic and proteomic methods to detect a cancer signal in the blood of people with solid tumours.\n\nThe registry record, read on 29 October 2026, gives its status as recruiting, with an estimated 20,000 participants, a start on 5 April 2018 and primary completion expected on 13 June 2029.","status":"recruiting","asOf":"2026-10-29","links":[{"label":"ClinicalTrials.gov NCT03869814","url":"https://clinicaltrials.gov/study/NCT03869814"}],"tags":[],"related":[],"cancers":[],"sections":["early-detection"],"technologies":["mced","liquid-biopsy"],"targets":[],"drugs":["avantect-mcd"],"companies":["clearnote-health"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT03869814","phase":"observational","setting":"People with solid tumours and controls in the United States, giving blood for genomic, epigenomic and protein analysis","sponsor":"ClearNote Health","started":"2018-04-05","startedType":"actual","enrolled":20000,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/clearnote-multi-cancer-epigenomics/","neighbours":{"section":[{"id":"early-detection","kind":"section","name":"Early Detection & Screening","route":"/fronts/early-detection/"}],"technology":[{"id":"liquid-biopsy","kind":"technology","name":"Liquid biopsy (ctDNA)","route":"/technologies/liquid-biopsy/"},{"id":"mced","kind":"technology","name":"Multi-cancer early detection (MCED)","route":"/technologies/mced/"}],"drug":[{"id":"avantect-mcd","kind":"drug","name":"Avantect Multi-Cancer Detection Test","route":"/drugs/avantect-mcd/"}],"company":[{"id":"clearnote-health","kind":"company","name":"ClearNote Health","route":"/companies/clearnote-health/"}]}}