{"entity":{"id":"curadel-pharma","kind":"company","name":"Curadel Surgical Innovations","aka":["Curadel Surgical Innovations B.V.","Curadel Surgical Innovations, Inc.","Curadel Pharma","Curadel"],"tldr":"Curadel Surgical Innovations holds European orphan status for CPI-008 (cRGD-ZW800-1), a dye that makes tumour tissue glow under near-infrared light during surgery, for head and neck cancer.","summary":"On 22 June 2026 the EMA granted orphan designation EU/3/26/3253 to cyclo(arginyl-glycyl-aspartyl-D-tyrosyl-lysyl)-nizaracianine-1, published as cRGD-ZW800-1, for the treatment of head and neck cancer, sponsored by Curadel Surgical Innovations B.V. (B.V. is the Dutch private-company form). Investigator-led phase 2 trials of the agent are registered at Erasmus Medical Center in oral cancer (NCT04191460) and in laryngeal and hypopharyngeal cancer (NCT05752149).","asOf":"2026-11-04","links":[{"label":"Company website","url":"https://www.curadelpharma.com/"},{"label":"EMA orphan designation EU/3/26/3253","url":"https://www.ema.europa.eu/en/medicines/human/orphan-designations/eu-3-26-3253"}],"tags":[],"related":[],"cancers":["head-and-neck"],"sections":["imaging","surgery"],"technologies":["fluorescence-guided-surgery"],"targets":[],"drugs":["cpi-008"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":["The company website refused automated reads (403) on 4 November 2026, so nothing it says about the company, its other programmes, funding or headquarters is recorded here; the record rests on the EMA designation and the trial registry."],"hq":"Not confirmed","country":"NL","companyType":"biotech","website":"https://www.curadelpharma.com/","stage":"startup","investors":[],"funding":[]},"route":"/companies/curadel-pharma/","neighbours":{"cancer":[{"id":"head-and-neck","kind":"cancer","name":"Head and neck squamous cell carcinoma","route":"/cancers/head-and-neck/"}],"section":[{"id":"imaging","kind":"section","name":"Imaging","route":"/fronts/imaging/"},{"id":"surgery","kind":"section","name":"Surgery & Interventional","route":"/fronts/surgery/"}],"technology":[{"id":"fluorescence-guided-surgery","kind":"technology","name":"Fluorescence-guided surgery","route":"/technologies/fluorescence-guided-surgery/"}],"drug":[{"id":"cpi-008","kind":"drug","name":"CPI-008","route":"/drugs/cpi-008/"}]}}