{"entity":{"id":"dazap1","kind":"target","name":"DAZAP1","aka":["DAZ associated protein 1","DAZ-associated protein 1","MGC19907"],"tldr":"DAZAP1 (DAZ-associated protein 1) is a gene. The public catalogues list it as a biomarker, and clinical evidence ties its variants to diagnosis, prognosis or drug response. Tied to Mantle cell lymphoma.","summary":"RNA-binding protein, which may be required during spermatogenesis.\n\nCIViC holds 1 clinical evidence item and 0 assertions across 1 variant.","asOf":"2026-09-23","links":[{"label":"HGNC HGNC:2683","url":"https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:2683"},{"label":"UniProt Q96EP5","url":"https://www.uniprot.org/uniprotkb/Q96EP5/entry"},{"label":"NCBI Gene 26528","url":"https://www.ncbi.nlm.nih.gov/gene/26528"},{"label":"Ensembl ENSG00000071626","url":"https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000071626"}],"tags":["cancer-genes-wave"],"related":["civic"],"cancers":["mantle-cell-lymphoma"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":["Written by scripts/fetch-cancer-genes.ts from CIViC, Open Targets, IntOGen, HGNC and UniProt; the function text is UniProt's, condensed and in UK spelling. Roles: CIViC holds 1 clinical evidence items on its variants. Evidence tier \"clinical-evidence\" is the strongest of those signals.","Prevalence not recorded: none of the sources gives a positivity rate."],"provenance":{"editedBy":"scripts/fetch-cancer-genes.ts (CIViC, Open Targets, IntOGen, HGNC, UniProt)","editedOn":"2026-09-23"},"symbol":"DAZAP1","role":["biomarker"],"evidenceTier":"clinical-evidence","sources":[{"label":"HGNC HGNC:2683","url":"https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:2683","note":"approved symbol, name, aliases, locus and cross-references (hgnc_complete_set.txt)"},{"label":"UniProt Q96EP5","url":"https://www.uniprot.org/uniprotkb/Q96EP5/entry","note":"protein name, function text, keywords and locations (REST API)"},{"label":"CIViC gene DAZAP1","url":"https://civicdb.org/features/10239","note":"1 evidence items, 0 assertions, 1 variants; diseases: Mantle Cell Lymphoma (GraphQL API, CC0)"}],"hgnc":"HGNC:2683","ensembl":"ENSG00000071626","uniprot":"Q96EP5","entrez":"26528","biology":"RNA-binding protein, which may be required during spermatogenesis. Location: Cytoplasm; Nucleus (UniProt). Locus 19p13.3 (HGNC).","whereFound":["Mantle cell lymphoma: CIViC evidence names this disease"],"targetClass":"other","prevalence":[]},"route":"/targets/dazap1/","neighbours":{"collection":[{"id":"civic","kind":"collection","name":"CIViC","route":"/collections/civic/"}],"cancer":[{"id":"mantle-cell-lymphoma","kind":"cancer","name":"Mantle cell lymphoma","route":"/cancers/mantle-cell-lymphoma/"}]}}