{"entity":{"id":"dfp-14323","kind":"drug","name":"DFP-14323","aka":[],"tldr":"DFP-14323 is an experimental small molecule from Delta-Fly Pharma, at a stage the company does not state for lung cancer; its current status is not stated.","summary":"DFP-14323 is a small molecule (oral; low-dose ubenimex, also called bestatin) from Delta-Fly Pharma, with Nippon Chemiphar as licensee. Low-dose ubenimex (bestatin), a protease inhibitor, which the company says has stronger anti-tumour effect and improves immune function; presented with an EGFR inhibitor in lung cancer. The company does not state its stage; it is aimed at lung cancer. No clinical trial naming it is registered on ClinicalTrials.gov. Stage not stated in the page text (the status chart is an image). No ClinicalTrials.gov record found; Japanese registries (jRCT) were not searched. It has not been shown to work in people.","asOf":"2026-11-03","links":[{"label":"Delta-Fly Pharma: delta-flypharma.co.jp","url":"https://www.delta-flypharma.co.jp/en/r-and-d"},{"label":"Delta-Fly Pharma: delta-flypharma.co.jp","url":"https://www.delta-flypharma.co.jp/en/r-and-d"}],"tags":["pipeline"],"related":[],"cancers":[],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":["delta-fly-pharma"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"provenance":{"editedBy":"OnCo gap audit, class 5 (company pipeline pages and ClinicalTrials.gov v2)","editedOn":"2026-11-03"},"code":"DFP-14323","modality":"Small molecule (oral; low-dose ubenimex, also called bestatin)","mechanism":"Low-dose ubenimex (bestatin), a protease inhibitor, which the company says has stronger anti-tumour effect and improves immune function; presented with an EGFR inhibitor in lung cancer.","approvals":[],"mechanismSteps":[],"toxicity":[],"access":[],"regulatoryEvents":[]},"route":"/drugs/dfp-14323/","neighbours":{"company":[{"id":"delta-fly-pharma","kind":"company","name":"Delta-Fly Pharma","route":"/companies/delta-fly-pharma/"}]}}