{"entity":{"id":"disc-medicine","kind":"company","name":"Disc Medicine","aka":["Disc Medicine, Inc"],"tldr":"Disc Medicine is a US-based biotechnology company that leads 2 cancer trials in OnCo, testing DISC-0974 and DISC-3405 in myeloproliferative neoplasms and myelodysplastic syndromes / neoplasms.","summary":"Disc Medicine is a clinical-stage biopharmaceutical company developing medicines for haematological diseases; its pipeline includes bitopertin, DISC-0974 and DISC-3405. On ClinicalTrials.gov it is the lead sponsor of 2 trials recorded in OnCo: NCT06985147 (phase 2, A Phase 2, Open-Label Study of DISC-3405 in Participants With Polycythemia Vera (PV)) and NCT05320198 (phase 1/2, Study of DISC-0974 (RALLY-MF) in Participants With Myelofibrosis or Myelodysplastic Syn...). Sponsor and trial facts are from the ClinicalTrials.gov registry; company facts are from the official website.","asOf":"2026-09-17","links":[{"label":"Official website","url":"https://www.discmedicine.com/"},{"label":"ClinicalTrials.gov: trials led by Disc Medicine","url":"https://clinicaltrials.gov/search?lead=Disc%20Medicine%2C%20Inc"}],"tags":["ctgov-sponsor"],"related":[],"cancers":["myeloproliferative-neoplasms","mds"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":["nct06985147","nct05320198"],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"provenance":{"editedBy":"OnCo orphan-trial linking round (ClinicalTrials.gov v2 + sponsor websites)","editedOn":"2026-09-17"},"hq":"Watertown, Massachusetts","country":"US","companyType":"biotech","website":"https://www.discmedicine.com/","ticker":"NASDAQ:IRON","stage":"public","investors":[],"funding":[]},"route":"/companies/disc-medicine/","neighbours":{"cancer":[{"id":"mds","kind":"cancer","name":"Myelodysplastic syndromes / neoplasms (MDS)","route":"/cancers/mds/"},{"id":"myeloproliferative-neoplasms","kind":"cancer","name":"Myeloproliferative neoplasms (PV, ET, myelofibrosis)","route":"/cancers/myeloproliferative-neoplasms/"}],"trial":[{"id":"nct06985147","kind":"trial","name":"A Phase 2, Open-Label Study of DISC-3405 in Participants With Polycythemia Vera (PV)","route":"/trials/nct06985147/"},{"id":"nct05320198","kind":"trial","name":"Study of DISC-0974 (RALLY-MF) in Participants With Myelofibrosis or Myelodysplastic Syndrome and Anemia","route":"/trials/nct05320198/"}]}}