{"entity":{"id":"dubravko-forcic","kind":"person","name":"Dubravko Forcic","aka":[],"tldr":"Dubravko Forcic is a Croatian virologist who works on vaccine virus strains and was joint first author of the 2024 self-experimental oncolytic virotherapy case report.","summary":"Dubravko Forcic works at the Centre for Research and Knowledge Transfer in Biotechnology at the University of Zagreb and at the Centre of Excellence for Virus Immunology and Vaccines. His published work concerns the vaccine virus strains made in Croatia, including the determination of the coding and non-coding nucleotide sequences of the Edmonston-Zagreb measles master seed and working seed lot, the strain used in paediatric vaccines for decades and the strain used in the 2024 case report.\n\nHe was joint first author, with the radiologist Karmen Mrsic, of the Vaccines case report describing self-experimental neoadjuvant oncolytic virotherapy in recurrent breast cancer, and shares its conceptualisation with Beata Halassy. Neither virus used in that protocol had been engineered for tumour selectivity; both were grown as clarified cell-culture supernatants in MRC-5 and Vero cells.","asOf":"2026-09-25","links":[{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Forcic%20D%5BAuthor%5D"},{"label":"University of Zagreb","url":"https://www.unizg.hr/"}],"tags":["virology","oncolytic-virus","croatia"],"related":[],"cancers":[],"sections":[],"technologies":["oncolytic-virus"],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":["beata-halassy"],"bottlenecks":[],"keyPapers":["paper-halassy-self-experiment-ovt-vaccines-2024"],"journals":[],"dependsOn":[],"notes":[],"role":"Virologist, Centre for Research and Knowledge Transfer in Biotechnology, University of Zagreb; Centre of Excellence for Virus Immunology and Vaccines, Zagreb","specialisms":["Virology","Measles and mumps vaccine strains","Virus genome sequencing","Oncolytic virotherapy"],"profiles":[{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Forcic%20D%5BAuthor%5D"},{"label":"University of Zagreb","url":"https://www.unizg.hr/"}],"papers":[{"title":"An unconventional case study of neoadjuvant oncolytic virotherapy for recurrent breast cancer","journal":"Vaccines","year":2024,"doi":"10.3390/vaccines12090958"},{"title":"Determination of the coding and non-coding nucleotide sequences of genuine Edmonston-Zagreb master seed and current working seed lot","journal":"Vaccine","year":2005,"doi":"10.1016/j.vaccine.2004.08.021"}]},"route":"/people/dubravko-forcic/","neighbours":{"technology":[{"id":"oncolytic-virus","kind":"technology","name":"Oncolytic viruses","route":"/technologies/oncolytic-virus/"}],"person":[{"id":"beata-halassy","kind":"person","name":"Beata Halassy","route":"/people/beata-halassy/"}],"paper":[{"id":"paper-halassy-self-experiment-ovt-vaccines-2024","kind":"paper","name":"The self-experiment: a virologist treated her own recurrent breast cancer with two viruses she made in her own laboratory","route":"/key-papers/paper-halassy-self-experiment-ovt-vaccines-2024/"}]}}