{"entity":{"id":"ellen-copson","kind":"person","name":"Ellen Copson","aka":[],"tldr":"First author of POSH, the UK prospective cohort of young-onset breast cancer that showed germline BRCA carriers did no worse than non-carriers, and the ones with triple-negative disease did better in the first two years.","summary":"Ellen Copson qualified from the United Medical and Dental Schools of Guy's and St Thomas' in 1996, trained in medical oncology in Southampton from 2001 and has been a consultant medical oncologist treating breast cancer at University Hospital Southampton since 2009, returning to academic medicine in 2012; the University of Southampton lists her as Professor Ellen Copson. Her consultant page describes a particular interest in familial breast cancer and its diagnosis and management. She was first author of POSH (Lancet Oncology 2018), the prospective cohort of 2,733 women diagnosed with breast cancer at 40 or under across 127 UK hospitals, which found no difference in overall survival between germline BRCA carriers and non-carriers, and a survival advantage for carriers with triple-negative disease in the first two years, evidence that informs the timing of risk-reducing surgery after a triple-negative diagnosis.","asOf":"2026-09-24","links":[{"label":"University Hospital Southampton consultant page","url":"https://www.uhs.nhs.uk/for-patients/find-your-consultant/dr-ellen-copson"},{"label":"University of Southampton profile","url":"https://www.southampton.ac.uk/people/5x2clr/professor-ellen-copson"}],"tags":["breast","oncogenetics","uk"],"related":["jean-abraham"],"cancers":["tnbc","breast-cancer"],"sections":[],"technologies":[],"targets":["brca"],"drugs":[],"companies":[],"institutions":["southampton-cancer"],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"role":"Professor of Medical Oncology, University of Southampton; Consultant Medical Oncologist (breast), University Hospital Southampton","institutionId":"southampton-cancer","specialisms":["Early and metastatic breast cancer","Familial and young-onset breast cancer","Oncogenetics","Host factors and treatment response"],"profiles":[{"label":"University Hospital Southampton consultant page","url":"https://www.uhs.nhs.uk/for-patients/find-your-consultant/dr-ellen-copson"},{"label":"University of Southampton profile","url":"https://www.southampton.ac.uk/people/5x2clr/professor-ellen-copson"}],"papers":[{"title":"Germline BRCA mutation and outcome in young-onset breast cancer (POSH): a prospective cohort study","journal":"Lancet Oncology","year":2018,"doi":"10.1016/s1470-2045(17)30891-4"}]},"route":"/people/ellen-copson/","neighbours":{"person":[{"id":"jean-abraham","kind":"person","name":"Jean Abraham","route":"/people/jean-abraham/"}],"cancer":[{"id":"breast-cancer","kind":"cancer","name":"Breast cancer (all types)","route":"/cancers/breast-cancer/"},{"id":"tnbc","kind":"cancer","name":"Triple-negative breast cancer (TNBC)","route":"/cancers/tnbc/"}],"target":[{"id":"brca","kind":"target","name":"BRCA1 / BRCA2 (HRD)","route":"/targets/brca/"}],"institution":[{"id":"southampton-cancer","kind":"institution","name":"University Hospital Southampton / Centre for Cancer Immunology","route":"/institutions/southampton-cancer/"}]}}