{"entity":{"id":"fgf20","kind":"target","name":"FGF20","aka":["fibroblast growth factor 20","Fibroblast growth factor 20"],"tldr":"FGF20 (Fibroblast growth factor 20) is a gene. In the public catalogues the evidence so far is association rather than a proven role.","summary":"Neurotrophic factor that regulates central nervous development and function.\n\nOpen Targets scores its association with cancer at 0.62 (direct and indirect evidence; datatypes literature 0.49, affected pathway 0.98, animal model 0.56, genetic association 0.05).","asOf":"2026-09-23","links":[{"label":"HGNC HGNC:3677","url":"https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:3677"},{"label":"UniProt Q9NP95","url":"https://www.uniprot.org/uniprotkb/Q9NP95/entry"},{"label":"NCBI Gene 26281","url":"https://www.ncbi.nlm.nih.gov/gene/26281"},{"label":"Ensembl ENSG00000078579","url":"https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000078579"}],"tags":["cancer-genes-wave"],"related":["open-targets"],"cancers":[],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":["Written by scripts/fetch-cancer-genes.ts from CIViC, Open Targets, IntOGen, HGNC and UniProt; the function text is UniProt's, condensed and in UK spelling. Roles: none stated by the sources. Evidence tier \"association-only\" is the strongest of those signals.","Prevalence not recorded: none of the sources gives a positivity rate."],"provenance":{"editedBy":"scripts/fetch-cancer-genes.ts (CIViC, Open Targets, IntOGen, HGNC, UniProt)","editedOn":"2026-09-23"},"symbol":"FGF20","role":[],"evidenceTier":"association-only","sources":[{"label":"HGNC HGNC:3677","url":"https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:3677","note":"approved symbol, name, aliases, locus and cross-references (hgnc_complete_set.txt)"},{"label":"UniProt Q9NP95","url":"https://www.uniprot.org/uniprotkb/Q9NP95/entry","note":"protein name, function text, keywords and locations (REST API)"},{"label":"Open Targets ENSG00000078579","url":"https://platform.opentargets.org/target/ENSG00000078579/associations","note":"association with cancer (MONDO_0004992) 0.62;  (GraphQL API, CC0)"}],"hgnc":"HGNC:3677","ensembl":"ENSG00000078579","uniprot":"Q9NP95","entrez":"26281","biology":"Neurotrophic factor that regulates central nervous development and function. Location: Secreted (UniProt). Locus 8p22 (HGNC).","whereFound":[],"targetClass":"other","prevalence":[]},"route":"/targets/fgf20/","neighbours":{"collection":[{"id":"open-targets","kind":"collection","name":"Open Targets Platform","route":"/collections/open-targets/"}]}}