{"entity":{"id":"fgf9","kind":"target","name":"FGF9","aka":["fibroblast growth factor 9","Fibroblast growth factor 9"],"tldr":"FGF9 (Fibroblast growth factor 9) is a gene. In the public catalogues the evidence so far is association rather than a proven role.","summary":"Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. May have a role in glial cell growth and differentiation during development, gliosis during repair and regeneration of brain tissue after damage, differentiation and survival of neuronal cells, and growth stimulation of glial tumours.\n\nOpen Targets scores its association with cancer at 0.67 (direct and indirect evidence; datatypes literature 0.98, affected pathway 0.99, animal model 0.85, genetic association 0.29).","asOf":"2026-09-23","links":[{"label":"HGNC HGNC:3687","url":"https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:3687"},{"label":"UniProt P31371","url":"https://www.uniprot.org/uniprotkb/P31371/entry"},{"label":"NCBI Gene 2254","url":"https://www.ncbi.nlm.nih.gov/gene/2254"},{"label":"Ensembl ENSG00000102678","url":"https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000102678"}],"tags":["cancer-genes-wave"],"related":["open-targets"],"cancers":[],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":["Written by scripts/fetch-cancer-genes.ts from CIViC, Open Targets, IntOGen, HGNC and UniProt; the function text is UniProt's, condensed and in UK spelling. Roles: none stated by the sources. Evidence tier \"association-only\" is the strongest of those signals.","Prevalence not recorded: none of the sources gives a positivity rate."],"provenance":{"editedBy":"scripts/fetch-cancer-genes.ts (CIViC, Open Targets, IntOGen, HGNC, UniProt)","editedOn":"2026-09-23"},"symbol":"FGF9","role":[],"evidenceTier":"association-only","sources":[{"label":"HGNC HGNC:3687","url":"https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:3687","note":"approved symbol, name, aliases, locus and cross-references (hgnc_complete_set.txt)"},{"label":"UniProt P31371","url":"https://www.uniprot.org/uniprotkb/P31371/entry","note":"protein name, function text, keywords and locations (REST API)"},{"label":"Open Targets ENSG00000102678","url":"https://platform.opentargets.org/target/ENSG00000102678/associations","note":"association with cancer (MONDO_0004992) 0.67;  (GraphQL API, CC0)"}],"hgnc":"HGNC:3687","ensembl":"ENSG00000102678","uniprot":"P31371","entrez":"2254","biology":"Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. May have a role in glial cell growth and differentiation during development, gliosis during repair and regeneration of brain tissue after damage, differentiation and survival of neuronal cells, and growth stimulation of glial tumours. Location: Secreted (UniProt). Locus 13q12.11 (HGNC).","whereFound":[],"targetClass":"other","prevalence":[]},"route":"/targets/fgf9/","neighbours":{"collection":[{"id":"open-targets","kind":"collection","name":"Open Targets Platform","route":"/collections/open-targets/"}]}}