{"entity":{"id":"galleri-unintentional-weight-loss","kind":"trial","name":"Galleri with weight tracking in unintentional weight loss (Case Comprehensive Cancer Center)","aka":[],"tldr":"A US study asking whether pairing the Galleri blood test with tracking of unexplained weight loss finds cancers earlier in people losing weight without trying.","summary":"Galleri with weight tracking in unintentional weight loss (NCT05481697) is a single-arm interventional study sponsored by Case Comprehensive Cancer Center with University Hospitals Seidman Cancer Center. Its primary outcome is the detection of cancers causing unintentional weight loss.\n\nThe registry record, read on 29 October 2026, gives its status as recruiting, with an estimated 1,000 participants, a start on 5 May 2023 and primary completion expected on 1 January 2027.","status":"recruiting","asOf":"2026-10-29","links":[{"label":"ClinicalTrials.gov NCT05481697","url":"https://clinicaltrials.gov/study/NCT05481697"}],"tags":[],"related":[],"cancers":[],"sections":["early-detection"],"technologies":["mced","liquid-biopsy"],"targets":[],"drugs":["galleri"],"companies":["grail"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT05481697","phase":"not-applicable","setting":"Adults with unintentional weight loss at one US centre, combining weekly weight tracking with the Galleri test","sponsor":"Case Comprehensive Cancer Center with University Hospitals Seidman Cancer Center","started":"2023-05-05","startedType":"actual","enrolled":1000,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/galleri-unintentional-weight-loss/","neighbours":{"section":[{"id":"early-detection","kind":"section","name":"Early Detection & Screening","route":"/fronts/early-detection/"}],"technology":[{"id":"liquid-biopsy","kind":"technology","name":"Liquid biopsy (ctDNA)","route":"/technologies/liquid-biopsy/"},{"id":"mced","kind":"technology","name":"Multi-cancer early detection (MCED)","route":"/technologies/mced/"}],"drug":[{"id":"galleri","kind":"drug","name":"Galleri","route":"/drugs/galleri/"}],"company":[{"id":"grail","kind":"company","name":"GRAIL","route":"/companies/grail/"}]}}