{"entity":{"id":"genecast","kind":"company","name":"Genecast Biotechnology","aka":["Genecast"],"tldr":"A Wuxi genomics company that co-developed TOTEM, a methylation blood test for seven cancers.","summary":"Genecast Biotechnology Co., Ltd., of Wuxi, Jiangsu, according to its authors' affiliations, co-developed TOTEM, a cell-free DNA methylation test for seven cancers with a predicted origin (BMC Cancer 2024).","asOf":"2026-11-03","links":[{"label":"TOTEM, BMC Cancer 2024","url":"https://doi.org/10.1186/s12885-024-12626-7"}],"tags":[],"related":[],"cancers":[],"sections":["early-detection","diagnostics"],"technologies":["mced","liquid-biopsy","cfdna-methylation-testing"],"targets":[],"drugs":["totem-genecast"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"hq":"Wuxi","country":"CN","companyType":"diagnostics","investors":[],"funding":[]},"route":"/companies/genecast/","neighbours":{"section":[{"id":"diagnostics","kind":"section","name":"Diagnostics & Biomarkers","route":"/fronts/diagnostics/"},{"id":"early-detection","kind":"section","name":"Early Detection & Screening","route":"/fronts/early-detection/"}],"technology":[{"id":"cfdna-methylation-testing","kind":"technology","name":"Cell-free DNA methylation tests","route":"/technologies/cfdna-methylation-testing/"},{"id":"liquid-biopsy","kind":"technology","name":"Liquid biopsy (ctDNA)","route":"/technologies/liquid-biopsy/"},{"id":"mced","kind":"technology","name":"Multi-cancer early detection (MCED)","route":"/technologies/mced/"}],"drug":[{"id":"totem-genecast","kind":"drug","name":"TOTEM (Genecast)","route":"/drugs/totem-genecast/"}],"paper":[{"id":"paper-totem-genecast-bmc-cancer-2024","kind":"paper","name":"TOTEM: a multi-cancer detection and localization approach using circulating tumor DNA methylation markers","route":"/key-papers/paper-totem-genecast-bmc-cancer-2024/"}]}}