{"entity":{"id":"h-and-e-staining","kind":"term","name":"H&E staining (haematoxylin and eosin)","aka":["H&E staining","H&E stain","H&E slide","H&E slides","haematoxylin and eosin","hematoxylin and eosin","H&E section"],"tldr":"H&E is the purple and pink stain on almost every pathology slide: haematoxylin colours cell nuclei blue-purple and eosin colours the cytoplasm and connective tissue pink.","summary":"Haematoxylin and eosin stain is one of the principal tissue stains in histology, the most widely used in medical diagnosis and often the gold standard; a biopsy of a suspected cancer will almost always be stained with H&E (Wikipedia). Because it is universal and cheap, digitised H&E slides are the input to pathology foundation models, which learn to predict grade, molecular alterations and outcome from morphology alone.","asOf":"2026-09-24","wikipedia":"https://en.wikipedia.org/wiki/H%26E_stain","links":[{"label":"Wikipedia","url":"https://en.wikipedia.org/wiki/H%26E_stain"}],"tags":["cansim-terms"],"related":["cancer-ai-vocabulary"],"cancers":[],"sections":[],"technologies":["histopathology-ihc","digital-pathology-ai"],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":["digital-pathology-wsi","tile-patch-encoding"],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":["Listed in the CanSim terms map 1.0.0 (docs/onco/terms.json, generated 2026-09-24), CC BY 4.0, attribution: CanSim project, an open, public-data-first cancer foundation-model programme; CanSim page path /terms/h-and-e-staining."],"provenance":{"editedBy":"OnCo CanSim terms wave (Wikipedia summaries, standards and project pages, GDC and FDA pages, Europe PMC)","editedOn":"2026-09-24","note":"CanSim terms map 1.0.0 (docs/onco/terms.json, generated 2026-09-24), CC BY 4.0, attribution: CanSim project, an open, public-data-first cancer foundation-model programme"},"category":"Pathology"},"route":"/terms/h-and-e-staining/","neighbours":{"term":[{"id":"cancer-ai-vocabulary","kind":"term","name":"Cancer AI vocabulary (CanSim terms map)","route":"/terms/cancer-ai-vocabulary/"},{"id":"digital-pathology-wsi","kind":"term","name":"Digital pathology and whole-slide images (WSI)","route":"/terms/digital-pathology-wsi/"},{"id":"tile-patch-encoding","kind":"term","name":"Tile and patch encoding of slides","route":"/terms/tile-patch-encoding/"}],"technology":[{"id":"digital-pathology-ai","kind":"technology","name":"Digital pathology & AI","route":"/technologies/digital-pathology-ai/"},{"id":"histopathology-ihc","kind":"technology","name":"Histopathology & immunohistochemistry","route":"/technologies/histopathology-ihc/"}]}}