{"entity":{"id":"hansjochen-wilke","kind":"person","name":"Hansjochen Wilke","aka":[],"tldr":"German oncologist who led RAINBOW, the trial that made ramucirumab plus paclitaxel a standard second-line treatment for advanced stomach cancer.","summary":"Hansjochen Wilke is a gastrointestinal oncologist at Kliniken Essen-Mitte. He was first author of the 2014 Lancet Oncology report of RAINBOW, which showed that adding the VEGFR2 antibody ramucirumab to paclitaxel lengthened overall survival compared with paclitaxel alone in advanced gastric or gastro-oesophageal junction adenocarcinoma after first-line therapy.","asOf":"2026-09-18","links":[],"tags":["gastric","trialist"],"related":[],"cancers":["gastric-pdl1-high","gastric"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":["kliniken-essen-mitte"],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":["paper-rainbow-ramucirumab-paclitaxel-lancet-oncol-2014"],"journals":[],"dependsOn":[],"notes":[],"role":"Medical oncologist, Kliniken Essen-Mitte","institutionId":"kliniken-essen-mitte","specialisms":["Gastric cancer","Anti-angiogenic therapy","Second-line chemotherapy"],"profiles":[{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Wilke%5BAuthor%5D"}],"papers":[]},"route":"/people/hansjochen-wilke/","neighbours":{"cancer":[{"id":"gastric","kind":"cancer","name":"Gastric & gastro-oesophageal junction cancer","route":"/cancers/gastric/"},{"id":"gastric-pdl1-high","kind":"cancer","name":"PD-L1-high gastric cancer","route":"/cancers/gastric-pdl1-high/"}],"institution":[{"id":"kliniken-essen-mitte","kind":"institution","name":"Kliniken Essen-Mitte","route":"/institutions/kliniken-essen-mitte/"}],"paper":[{"id":"paper-rainbow-ramucirumab-paclitaxel-lancet-oncol-2014","kind":"paper","name":"RAINBOW: ramucirumab plus paclitaxel versus placebo plus paclitaxel in previously treated advanced gastric cancer","route":"/key-papers/paper-rainbow-ramucirumab-paclitaxel-lancet-oncol-2014/"}]}}