{"entity":{"id":"hgnc-symbol","kind":"term","name":"HGNC gene symbol","aka":["HGNC symbol","HGNC gene symbol","approved gene symbol","official gene symbol","gene symbol","HGNC id","HGNC ID"],"tldr":"The HGNC symbol is the one official short name for each human gene (ERBB2, not HER2 or NEU), so that datasets can be joined without guessing.","summary":"The HUGO Gene Nomenclature Committee approves a unique name and symbol for every known human gene (Wikipedia). Symbols change and aliases collide (HER2 is ERBB2; the symbol MLL became KMT2A), so every dataset should carry the stable HGNC ID (HGNC:3430) as well as the symbol, and gene lists from different years must be mapped before they are joined. OnCo's target records carry HGNC, Ensembl, UniProt and Entrez identifiers for this reason.","asOf":"2026-09-24","wikipedia":"https://en.wikipedia.org/wiki/HUGO_Gene_Nomenclature_Committee","links":[{"label":"HGNC (genenames.org)","url":"https://www.genenames.org/about/"},{"label":"Wikipedia","url":"https://en.wikipedia.org/wiki/HUGO_Gene_Nomenclature_Committee"}],"tags":["cansim-terms"],"related":["her2","cancer-ai-vocabulary"],"cancers":[],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":["ensembl-gene-id","genome-builds"],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":["Listed in the CanSim terms map 1.0.0 (docs/onco/terms.json, generated 2026-09-24), CC BY 4.0, attribution: CanSim project, an open, public-data-first cancer foundation-model programme; CanSim page path /terms/hgnc-symbol."],"provenance":{"editedBy":"OnCo CanSim terms wave (Wikipedia summaries, standards and project pages, GDC and FDA pages, Europe PMC)","editedOn":"2026-09-24","note":"CanSim terms map 1.0.0 (docs/onco/terms.json, generated 2026-09-24), CC BY 4.0, attribution: CanSim project, an open, public-data-first cancer foundation-model programme"},"category":"Genomics & genetics"},"route":"/terms/hgnc-symbol/","neighbours":{"target":[{"id":"her2","kind":"target","name":"HER2","route":"/targets/her2/"}],"term":[{"id":"cancer-ai-vocabulary","kind":"term","name":"Cancer AI vocabulary (CanSim terms map)","route":"/terms/cancer-ai-vocabulary/"},{"id":"ensembl-gene-id","kind":"term","name":"Ensembl gene ID","route":"/terms/ensembl-gene-id/"},{"id":"genome-builds","kind":"term","name":"Genome builds: GRCh38 versus hg19 (GRCh37)","route":"/terms/genome-builds/"}]}}