{"entity":{"id":"hs-10502","kind":"drug","name":"HS-10502","aka":[],"tldr":"HS-10502 is an experimental pill being studied to block a DNA-repair enzyme in cancer cells.","summary":"The registry describes HS-10502 as a PARP1-specific selective inhibitor. The linked registry records distinguish recruiting, closed, and discontinued studies; those states do not establish comparative efficacy or approval.","status":"phase-1","asOf":"2026-10-06","links":[{"label":"ClinicalTrials.gov NCT05740956","url":"https://clinicaltrials.gov/study/NCT05740956"},{"label":"ClinicalTrials.gov NCT06769425","url":"https://clinicaltrials.gov/study/NCT06769425"}],"tags":[],"related":[],"cancers":["breast-cancer","ovarian","prostate","pancreatic","colorectal","tnbc","gastric"],"sections":[],"technologies":[],"targets":["parp"],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":["nct05740956","nct06769425"],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"modality":"Small-molecule PARP1 inhibitor","mechanism":"The registry describes HS-10502 as a PARP1-specific selective inhibitor.","approvals":[],"mechanismSteps":[],"toxicity":[],"access":[],"regulatoryEvents":[]},"route":"/drugs/hs-10502/","neighbours":{"cancer":[{"id":"breast-cancer","kind":"cancer","name":"Breast cancer (all types)","route":"/cancers/breast-cancer/"},{"id":"colorectal","kind":"cancer","name":"Colorectal cancer","route":"/cancers/colorectal/"},{"id":"gastric","kind":"cancer","name":"Gastric & gastro-oesophageal junction cancer","route":"/cancers/gastric/"},{"id":"ovarian","kind":"cancer","name":"Ovarian cancer","route":"/cancers/ovarian/"},{"id":"pancreatic","kind":"cancer","name":"Pancreatic ductal adenocarcinoma","route":"/cancers/pancreatic/"},{"id":"prostate","kind":"cancer","name":"Prostate cancer","route":"/cancers/prostate/"},{"id":"tnbc","kind":"cancer","name":"Triple-negative breast cancer (TNBC)","route":"/cancers/tnbc/"}],"target":[{"id":"parp","kind":"target","name":"PARP","route":"/targets/parp/"}],"trial":[{"id":"nct05740956","kind":"trial","name":"A Study of Hansoh (HS)-10502 in Patients With Advanced Solid Tumors","route":"/trials/nct05740956/"},{"id":"nct06769425","kind":"trial","name":"HS-10502 Combination Treatment in Patients With Advanced Solid Tumors","route":"/trials/nct06769425/"}]}}