{"entity":{"id":"icecure-medical","kind":"company","name":"IceCure Medical","aka":[],"tldr":"IceCure Medical makes ProSense, a liquid-nitrogen cryoablation system used to freeze small breast, kidney, lung and bone tumours through a single needle in an outpatient visit; its ICE3 trial tested it as an alternative to surgery for small low-risk breast cancers in older women.","summary":"IceCure Medical, founded in Israel in 2006, designed ProSense around liquid nitrogen rather than argon to reach very low probe temperatures and larger ice balls with a single thin probe, under ultrasound guidance in an office setting. The ICE3 single-arm trial followed women aged sixty and over with small low-risk breast cancers treated by cryoablation instead of lumpectomy, and the company is pursuing a breast cancer indication in the United States on those results while the system is used for kidney, lung, liver and bone tumours. OnCo links it to cryoablation and thermal ablation.","asOf":"2026-09-17","links":[{"label":"Official website","url":"https://www.icecure-medical.com"}],"tags":["machines-wave"],"related":[],"cancers":["breast-cancer","rcc"],"sections":["surgery","devices"],"technologies":["cryoablation-systems","thermal-ablation"],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"hq":"Caesarea","country":"IL","companyType":"devices","website":"https://www.icecure-medical.com","ticker":"ICCM","founded":2006,"stage":"public","investors":[],"funding":[]},"route":"/companies/icecure-medical/","neighbours":{"cancer":[{"id":"breast-cancer","kind":"cancer","name":"Breast cancer (all types)","route":"/cancers/breast-cancer/"},{"id":"rcc","kind":"cancer","name":"Renal cell carcinoma","route":"/cancers/rcc/"}],"section":[{"id":"devices","kind":"section","name":"Devices & Physical Therapies","route":"/fronts/devices/"},{"id":"surgery","kind":"section","name":"Surgery & Interventional","route":"/fronts/surgery/"}],"technology":[{"id":"cryoablation-systems","kind":"technology","name":"Cryoablation systems","route":"/technologies/cryoablation-systems/"},{"id":"thermal-ablation","kind":"technology","name":"Thermal ablation (RFA, microwave, cryo)","route":"/technologies/thermal-ablation/"}]}}