{"entity":{"id":"iohexol","kind":"drug","name":"Iohexol","aka":["iohexol","Omnipaque"],"tldr":"One of the commonest dyes used for CT scans, given into a vein, by mouth or in other ways depending on the scan.","summary":"GE Healthcare's Omnipaque (NDA 018956, first approved 26 December 1985) \"is a radiographic contrast agent indicated for intrathecal, intra-arterial, intravenous, oral, rectal, intraarticular, and body cavity imaging procedures in adults and pediatric patients\"; intravenous indications include \"CT of the head and body\". Its boxed warning concerns using only the iodine concentrations recommended for intrathecal procedures. ATC V08AB02.","status":"approved","asOf":"2026-11-04","links":[{"label":"Drugs@FDA Omnipaque (NDA 018956)","url":"https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=018956"},{"label":"DailyMed label: Omnipaque","url":"https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=5088be1d-a708-1cac-e063-6394a90a2aff"},{"label":"WHO ATC index V08AB: low osmolar X-ray contrast media","url":"https://atcddd.fhi.no/atc_ddd_index/?code=V08AB&showdescription=no"}],"tags":["contrast-agents-gaps-2026-11","diagnostic"],"related":[],"cancers":[],"sections":[],"technologies":["iodinated-contrast-media","ct"],"targets":[],"drugs":[],"companies":["ge-healthcare"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"provenance":{"editedBy":"OnCo contrast agent gap fill (Drugs@FDA, FDA labels, DailyMed, EMA register, WHO ATC index)","editedOn":"2026-11-04"},"brand":"Omnipaque","modality":"Iodinated contrast agent for CT and X-ray imaging (intravenous, intra-arterial, intrathecal, oral, rectal)","mechanism":"A non-ionic, low-osmolar iodinated molecule; iodine absorbs X-rays strongly, so blood vessels, organs and enhancing tumours appear bright on CT and X-ray.","approvals":[{"region":"US","year":1985,"indication":"Intrathecal, intra-arterial, intravenous, oral, rectal, intra-articular and body cavity imaging, including CT of the head and body","note":"NDA 018956; GE Healthcare"}],"mechanismSteps":[],"toxicity":[],"access":[],"regulatoryEvents":[]},"route":"/drugs/iohexol/","neighbours":{"technology":[{"id":"ct","kind":"technology","name":"CT (computed tomography)","route":"/technologies/ct/"},{"id":"iodinated-contrast-media","kind":"technology","name":"Iodinated and barium contrast for CT and X-ray","route":"/technologies/iodinated-contrast-media/"}],"company":[{"id":"ge-healthcare","kind":"company","name":"GE HealthCare","route":"/companies/ge-healthcare/"}]}}