{"entity":{"id":"iotn","kind":"institution","name":"Immuno-Oncology Translational Network (IOTN)","aka":["IOTN","NCI Immuno-Oncology Translational Network"],"tldr":"A US National Cancer Institute network, paid for by the Cancer Moonshot, that works to turn lab discoveries about the immune system into better immunotherapy for adults with cancer and into ways of preventing cancer with the immune system.","summary":"The network describes itself as a consortium to accelerate the translation of basic discoveries into clinical applications that improve immunotherapy outcomes, and to prevent cancers before they occur, by drawing on the expertise and resources of a collaborative network to develop improved immunotherapy and immunoprevention approaches, including new combinations. Its project groups, as its site lists them, are cancer immunoprevention, cancer immunotherapy, cancer immuno-engineering and immune-related adverse events, with a cellular immunotherapy data resource and a data management and resource-sharing centre. The NCI's Cancer Moonshot page lists it among the Moonshot's accomplishments as an immuno-oncology translational network to develop immune-based approaches for the treatment and prevention of cancer in adult patients.","asOf":"2026-11-04","links":[{"label":"IOTN","url":"https://www.iotnmoonshot.org/en/"},{"label":"NCI: The Cancer Moonshot","url":"https://www.cancer.gov/research/progress/moonshot-cancer-initiative"}],"tags":["research-funding"],"related":[],"cancers":[],"sections":["immunotherapy"],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":["nci"],"pathways":[],"terms":["irae"],"trials":[],"people":[],"bottlenecks":["b-immunotherapy-response"],"keyPapers":[],"journals":[],"dependsOn":[],"notes":["Placed at NCI in Bethesda: the pages read name no coordinating institution. Member sites, award numbers and funding totals were not stated on the pages read and are left out."],"city":"Bethesda, MD","country":"US","lat":39.003,"lng":-77.104,"institutionType":"consortium","website":"https://www.iotnmoonshot.org/en/","programs":["Cancer immunoprevention projects","Cancer immunotherapy projects","Cancer immuno-engineering projects","Immune-related adverse event projects","Cellular Immunotherapy Data Resource","Data Management and Resource-Sharing Center"]},"route":"/institutions/iotn/","neighbours":{"section":[{"id":"immunotherapy","kind":"section","name":"Immunotherapy","route":"/fronts/immunotherapy/"}],"institution":[{"id":"nci","kind":"institution","name":"National Cancer Institute (NIH)","route":"/institutions/nci/"}],"term":[{"id":"irae","kind":"term","name":"Immune-related adverse events (irAEs)","route":"/terms/irae/"}],"bottleneck":[{"id":"b-immunotherapy-response","kind":"bottleneck","name":"No one can predict who responds to immunotherapy","route":"/bottlenecks/b-immunotherapy-response/"}]}}