{"entity":{"id":"jmbi-001","kind":"drug","name":"JMBI-001","aka":[],"tldr":"JMBI-001 is an experimental oral tablet from Anticancer Bioscience, in phase 1 trials for MYC-positive advanced solid tumours and relapsed or refractory non-Hodgkin lymphoma.","summary":"JMBI-001 is an oral tablet (small molecule not stated) from Anticancer Bioscience, with Peking University Cancer Hospital & Institute as partner. Tested in adults with MYC-positive advanced cancers; the company describes its work as MYC synthetic lethality, but no source states JMBI-001's molecular target. Its furthest stage is phase 1, for MYC-positive advanced solid tumours and relapsed or refractory non-Hodgkin lymphoma. ClinicalTrials.gov registers it in one study linked below. Phase 1/2 recruiting, start October 2026 (NCT07864701). Whether it works in people has not been established unless a trial below reports it.","status":"phase-1","asOf":"2026-11-03","links":[{"label":"Anticancer Bioscience: clinicaltrials.gov","url":"https://clinicaltrials.gov/study/NCT07864701"},{"label":"Anticancer Bioscience: anticancerbio.com","url":"https://www.anticancerbio.com/"},{"label":"ClinicalTrials.gov: trials of JMBI-001","url":"https://clinicaltrials.gov/search?intr=JMBI-001"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["metastatic-cancer","non-hodgkin-lymphoma"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":["anticancer-bioscience"],"institutions":[],"pathways":[],"terms":[],"trials":["nct07864701"],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"provenance":{"editedBy":"OnCo gap audit, class 5 (company pipeline pages and ClinicalTrials.gov v2)","editedOn":"2026-11-03"},"code":"JMBI-001","modality":"Oral tablet (small molecule not stated)","mechanism":"Tested in adults with MYC-positive advanced cancers; the company describes its work as MYC synthetic lethality, but no source states JMBI-001's molecular target.","approvals":[],"mechanismSteps":[],"toxicity":[],"access":[],"regulatoryEvents":[]},"route":"/drugs/jmbi-001/","neighbours":{"cancer":[{"id":"metastatic-cancer","kind":"cancer","name":"Metastatic cancer (cancer that has spread)","route":"/cancers/metastatic-cancer/"},{"id":"non-hodgkin-lymphoma","kind":"cancer","name":"Non-Hodgkin lymphoma (all types)","route":"/cancers/non-hodgkin-lymphoma/"}],"company":[{"id":"anticancer-bioscience","kind":"company","name":"Anticancer Bioscience","route":"/companies/anticancer-bioscience/"}],"trial":[{"id":"nct07864701","kind":"trial","name":"Study of JMBI-001 in Patients With MYC-Positive Advanced Cancers","route":"/trials/nct07864701/"}]}}