{"entity":{"id":"karen-knudsen","kind":"person","name":"Karen E. Knudsen","aka":[],"tldr":"The cancer biologist and former American Cancer Society chief executive who now runs the Parker Institute for Cancer Immunotherapy.","summary":"Karen Knudsen is Chief Executive Officer and a board member of the Parker Institute for Cancer Immunotherapy, which describes her as a globally recognised cancer scientist and executive leader focused on turning all cancers into curable diseases. Before joining PICI in 2024 she was Chief Executive Officer of the American Cancer Society and its advocacy arm, and earlier directed the Sidney Kimmel Cancer Center at Thomas Jefferson University in Philadelphia. Her own research concerned prostate cancer, in particular the androgen receptor and DNA repair. Her publications are listed on PubMed.","asOf":"2026-09-17","links":[{"label":"PICI profile","url":"https://www.parkerici.org/person/karen-e-knudsen/"},{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Knudsen+KE%5BAuthor%5D+prostate"}],"tags":["leadership","immunotherapy"],"related":[],"cancers":["prostate"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":["parker-institute"],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"role":"Chief Executive Officer and Board Member, Parker Institute for Cancer Immunotherapy","institutionId":"parker-institute","specialisms":["Prostate cancer biology","Cancer centre leadership","Research strategy and partnerships"],"profiles":[{"label":"PICI profile","url":"https://www.parkerici.org/person/karen-e-knudsen/"},{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Knudsen+KE%5BAuthor%5D+prostate"}],"papers":[{"title":"DNA-Repair Defects and Olaparib in Metastatic Prostate Cancer","journal":"New England Journal of Medicine","year":2015,"url":"https://doi.org/10.1056/NEJMoa1506859","doi":"10.1056/NEJMoa1506859","note":"Europe PMC author record matched by affiliation"},{"title":"Prostate cancer","journal":"Nature Reviews Disease Primers","year":2021,"url":"https://doi.org/10.1038/s41572-020-00243-0","doi":"10.1038/s41572-020-00243-0","note":"Europe PMC author record matched by affiliation"},{"title":"Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer","journal":"Cell","year":2018,"url":"https://doi.org/10.1016/j.cell.2018.06.039","doi":"10.1016/j.cell.2018.06.039","note":"Europe PMC author record matched by affiliation"}]},"route":"/people/karen-knudsen/","neighbours":{"cancer":[{"id":"prostate","kind":"cancer","name":"Prostate cancer","route":"/cancers/prostate/"}],"institution":[{"id":"parker-institute","kind":"institution","name":"Parker Institute for Cancer Immunotherapy","route":"/institutions/parker-institute/"}]}}