{"entity":{"id":"krishnansu-tewari","kind":"person","name":"Krishnansu S. Tewari","aka":[],"tldr":"California gynaecologic oncologist who led GOG 240, the trial that made bevacizumab the first targeted drug to lengthen survival in advanced cervical cancer, and EMPOWER-Cervical 1, which did the same for the PD-1 antibody cemiplimab.","summary":"Krishnansu Tewari is a gynaecologic oncologist at the University of California, Irvine. He was first author of the 2014 New England Journal of Medicine report of GOG 240, in which adding bevacizumab to chemotherapy improved overall survival in recurrent, persistent or metastatic cervical cancer, and of the 2022 New England Journal of Medicine report of EMPOWER-Cervical 1, in which cemiplimab lengthened survival compared with chemotherapy after platinum failure.","asOf":"2026-09-18","links":[],"tags":["cervical","gynaecological","trialist"],"related":[],"cancers":["recurrent-metastatic-cervical-cancer","cervical"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":["uci-chao"],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":["paper-empower-cervical-1-cemiplimab-nejm-2022","paper-gog-240-bevacizumab-cervical-nejm-2014"],"journals":[],"dependsOn":[],"notes":[],"role":"Gynaecologic oncologist, Chao Family Comprehensive Cancer Center, UC Irvine","institutionId":"uci-chao","specialisms":["Cervical cancer","Anti-angiogenic therapy","Immunotherapy"],"profiles":[{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Tewari%5BAuthor%5D"}],"papers":[]},"route":"/people/krishnansu-tewari/","neighbours":{"cancer":[{"id":"cervical","kind":"cancer","name":"Cervical cancer","route":"/cancers/cervical/"},{"id":"recurrent-metastatic-cervical-cancer","kind":"cancer","name":"Recurrent or metastatic cervical cancer","route":"/cancers/recurrent-metastatic-cervical-cancer/"}],"institution":[{"id":"uci-chao","kind":"institution","name":"Chao Family Comprehensive Cancer Center, UC Irvine","route":"/institutions/uci-chao/"}],"paper":[{"id":"paper-empower-cervical-1-cemiplimab-nejm-2022","kind":"paper","name":"EMPOWER-Cervical 1: cemiplimab versus chemotherapy in recurrent cervical cancer after platinum","route":"/key-papers/paper-empower-cervical-1-cemiplimab-nejm-2022/"},{"id":"paper-gog-240-bevacizumab-cervical-nejm-2014","kind":"paper","name":"GOG 240: bevacizumab added to chemotherapy for advanced cervical cancer","route":"/key-papers/paper-gog-240-bevacizumab-cervical-nejm-2014/"}]}}