{"entity":{"id":"leibovich-score","kind":"term","name":"Leibovich score (kidney cancer recurrence risk after surgery)","aka":["Leibovich score","Leibovich risk"],"tldr":"The Leibovich score predicts how likely clear cell kidney cancer is to spread after the kidney is removed, and it is used to decide who is offered treatment after surgery.","summary":"In 1,671 patients with localised clear cell renal cell carcinoma treated by radical nephrectomy from 1970 to 2000, Leibovich and colleagues (Cancer 2003) found five features linked to later metastasis: tumour stage, regional lymph node status, tumour size, nuclear grade and tumour necrosis. They combined them into a scoring algorithm to stratify patients for adjuvant therapy trials. Metastasis-free survival across the whole cohort was 74.1% at five years.","asOf":"2026-11-04","links":[{"label":"Leibovich et al., Prediction of progression after radical nephrectomy for patients with clear cell renal cell carcinoma (Cancer 2003)","url":"https://doi.org/10.1002/cncr.11234"}],"tags":[],"related":["mskcc-motzer-rcc","imdc-risk"],"cancers":["clear-cell-rcc","rcc"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"category":"Clinical"},"route":"/terms/leibovich-score/","neighbours":{"term":[{"id":"staging-systems","kind":"term","name":"Disease-specific staging and risk systems (FIGO, Ann Arbor, IPI, R-ISS, ELN, IMDC)","route":"/terms/staging-systems/"},{"id":"imdc-risk","kind":"term","name":"IMDC risk groups (favourable / intermediate / poor)","route":"/terms/imdc-risk/"},{"id":"mskcc-motzer-rcc","kind":"term","name":"MSKCC (Motzer) risk groups for advanced kidney cancer","route":"/terms/mskcc-motzer-rcc/"}],"cancer":[{"id":"clear-cell-rcc","kind":"cancer","name":"Clear cell renal cell carcinoma","route":"/cancers/clear-cell-rcc/"},{"id":"rcc","kind":"cancer","name":"Renal cell carcinoma","route":"/cancers/rcc/"}]}}