{"entity":{"id":"liv-2008-2008b","kind":"drug","name":"LIV-2008/2008b","aka":["LIV-2008","LIV-2008b"],"tldr":"LIV-2008/2008b is an experimental humanized monoclonal antibody from Chiome Bioscience, in preclinical development for triple-negative breast cancer, lung cancer and colorectal cancer.","summary":"LIV-2008/2008b (LIV-2008, LIV-2008b) is a humanized monoclonal antibody from Chiome Bioscience. A humanized anti-TROP-2 (TROP2) antibody generated by hybridoma technology. Its furthest stage is preclinical development, for triple-negative breast cancer, lung cancer and colorectal cancer. No clinical trial naming it is registered on ClinicalTrials.gov. Listed as 'Licensing opportunity'. It has not been shown to work in people.","status":"preclinical","asOf":"2026-11-03","links":[{"label":"Chiome Bioscience: chiome.co.jp","url":"https://www.chiome.co.jp/en/pipeline/"}],"tags":["pipeline"],"related":[],"cancers":[],"sections":[],"technologies":[],"targets":["trop2"],"drugs":[],"companies":["chiome-bioscience"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"provenance":{"editedBy":"OnCo gap audit, class 5 (company pipeline pages and ClinicalTrials.gov v2)","editedOn":"2026-11-03"},"code":"LIV-2008/2008b","modality":"Humanized monoclonal antibody","mechanism":"A humanized anti-TROP-2 (TROP2) antibody generated by hybridoma technology.","approvals":[],"mechanismSteps":[],"toxicity":[],"access":[],"regulatoryEvents":[]},"route":"/drugs/liv-2008-2008b/","neighbours":{"target":[{"id":"trop2","kind":"target","name":"TROP2","route":"/targets/trop2/"}],"company":[{"id":"chiome-bioscience","kind":"company","name":"Chiome Bioscience","route":"/companies/chiome-bioscience/"}]}}