{"entity":{"id":"lmo7","kind":"target","name":"LMO7","aka":["LIM domain 7","LIM domain only protein 7","FBX20","KIAA0858","FBXO20"],"tldr":"LMO7 (LIM domain only protein 7) is a gene. In the public catalogues the evidence so far is association rather than a proven role.","summary":"UniProt has no function text for Q8WWI1; HGNC names it \"LIM domain 7\".\n\nOpen Targets scores its association with cancer at 0.57 (direct and indirect evidence; datatypes literature 0.45, affected pathway 0.76, animal model 0.80, genetic association 0.48).","asOf":"2026-09-23","links":[{"label":"HGNC HGNC:6646","url":"https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:6646"},{"label":"UniProt Q8WWI1","url":"https://www.uniprot.org/uniprotkb/Q8WWI1/entry"},{"label":"NCBI Gene 4008","url":"https://www.ncbi.nlm.nih.gov/gene/4008"},{"label":"Ensembl ENSG00000136153","url":"https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000136153"}],"tags":["cancer-genes-wave"],"related":["open-targets"],"cancers":[],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":["Written by scripts/fetch-cancer-genes.ts from CIViC, Open Targets, IntOGen, HGNC and UniProt; the function text is UniProt's, condensed and in UK spelling. Roles: none stated by the sources. Evidence tier \"association-only\" is the strongest of those signals.","Prevalence not recorded: none of the sources gives a positivity rate."],"provenance":{"editedBy":"scripts/fetch-cancer-genes.ts (CIViC, Open Targets, IntOGen, HGNC, UniProt)","editedOn":"2026-09-23"},"symbol":"LMO7","role":[],"evidenceTier":"association-only","sources":[{"label":"HGNC HGNC:6646","url":"https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:6646","note":"approved symbol, name, aliases, locus and cross-references (hgnc_complete_set.txt)"},{"label":"UniProt Q8WWI1","url":"https://www.uniprot.org/uniprotkb/Q8WWI1/entry","note":"protein name, function text, keywords and locations (REST API)"},{"label":"Open Targets ENSG00000136153","url":"https://platform.opentargets.org/target/ENSG00000136153/associations","note":"association with cancer (MONDO_0004992) 0.57;  (GraphQL API, CC0)"}],"hgnc":"HGNC:6646","ensembl":"ENSG00000136153","uniprot":"Q8WWI1","entrez":"4008","biology":"UniProt has no function text for Q8WWI1; HGNC names it \"LIM domain 7\". Locus 13q22.2 (HGNC).","whereFound":[],"targetClass":"other","prevalence":[]},"route":"/targets/lmo7/","neighbours":{"collection":[{"id":"open-targets","kind":"collection","name":"Open Targets Platform","route":"/collections/open-targets/"}]}}