{"entity":{"id":"mageh1","kind":"target","name":"MAGEH1","aka":["MAGE family member H1","Melanoma-associated antigen H1","APR1"],"tldr":"MAGEH1 (Melanoma-associated antigen H1) is a gene. The public catalogues list it as a drug target and a biomarker, and clinical evidence ties its variants to diagnosis, prognosis or drug response.","summary":"UniProt has no function text for Q9H213; HGNC names it \"MAGE family member H1\".\n\nCIViC holds 1 clinical evidence item and 0 assertions across 1 variant, naming Gemcitabine.","asOf":"2026-09-23","links":[{"label":"HGNC HGNC:24092","url":"https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:24092"},{"label":"UniProt Q9H213","url":"https://www.uniprot.org/uniprotkb/Q9H213/entry"},{"label":"NCBI Gene 28986","url":"https://www.ncbi.nlm.nih.gov/gene/28986"},{"label":"Ensembl ENSG00000187601","url":"https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000187601"}],"tags":["cancer-genes-wave"],"related":["civic"],"cancers":[],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":["Written by scripts/fetch-cancer-genes.ts from CIViC, Open Targets, IntOGen, HGNC and UniProt; the function text is UniProt's, condensed and in UK spelling. Roles: CIViC lists 1 therapies; CIViC holds 1 clinical evidence items on its variants. Evidence tier \"clinical-evidence\" is the strongest of those signals.","Prevalence not recorded: none of the sources gives a positivity rate.","Diseases the sources name that have no OnCo cancer page yet, so they are not linked: Bile Duct Adenocarcinoma."],"provenance":{"editedBy":"scripts/fetch-cancer-genes.ts (CIViC, Open Targets, IntOGen, HGNC, UniProt)","editedOn":"2026-09-23"},"symbol":"MAGEH1","role":["drug-target","biomarker"],"evidenceTier":"clinical-evidence","sources":[{"label":"HGNC HGNC:24092","url":"https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:24092","note":"approved symbol, name, aliases, locus and cross-references (hgnc_complete_set.txt)"},{"label":"UniProt Q9H213","url":"https://www.uniprot.org/uniprotkb/Q9H213/entry","note":"protein name, function text, keywords and locations (REST API)"},{"label":"CIViC gene MAGEH1","url":"https://civicdb.org/features/11261","note":"1 evidence items, 0 assertions, 1 variants; diseases: Bile Duct Adenocarcinoma (GraphQL API, CC0)"}],"hgnc":"HGNC:24092","ensembl":"ENSG00000187601","uniprot":"Q9H213","entrez":"28986","biology":"UniProt has no function text for Q9H213; HGNC names it \"MAGE family member H1\". Locus Xp11.21 (HGNC).","whereFound":[],"targetClass":"other","prevalence":[]},"route":"/targets/mageh1/","neighbours":{"collection":[{"id":"civic","kind":"collection","name":"CIViC","route":"/collections/civic/"}]}}