{"entity":{"id":"maria-de-santis","kind":"person","name":"Maria De Santis","aka":[],"tldr":"Berlin oncologist who led SEMPET, the study showing that a PET scan can tell which residual masses after chemotherapy for seminoma still contain cancer, sparing many men further treatment.","summary":"Maria De Santis is a genitourinary medical oncologist at Charité in Berlin. She was first author of the 2004 Journal of Clinical Oncology report of the SEMPET study, which showed that FDG-PET reliably distinguished viable tumour from fibrosis in residual masses after chemotherapy for seminoma, particularly for masses over 3 cm, a finding adopted into guidelines. She is also a leading investigator in urothelial cancer and chairs the EAU testis cancer guideline panel.","asOf":"2026-09-18","links":[],"tags":["testis","imaging","trialist"],"related":[],"cancers":["seminoma"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":["charite"],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":["paper-sempet-de-santis-jco-2004"],"journals":[],"dependsOn":[],"notes":[],"role":"Genitourinary medical oncologist, Charité Universitätsmedizin Berlin","institutionId":"charite","specialisms":["Germ cell tumours","Bladder cancer","Positron emission tomography in oncology"],"profiles":[{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Santis%5BAuthor%5D"}],"papers":[],"orcid":"0000-0003-4969-0877"},"route":"/people/maria-de-santis/","neighbours":{"cancer":[{"id":"seminoma","kind":"cancer","name":"Seminoma","route":"/cancers/seminoma/"}],"institution":[{"id":"charite","kind":"institution","name":"Charité Universitätsmedizin Berlin","route":"/institutions/charite/"}],"paper":[{"id":"paper-sempet-de-santis-jco-2004","kind":"paper","name":"SEMPET: FDG-PET as a predictor of viable tumour in post-chemotherapy seminoma residuals","route":"/key-papers/paper-sempet-de-santis-jco-2004/"}]}}