{"entity":{"id":"matrisome-bio","kind":"company","name":"Matrisome Bio","aka":["MATRISOME BIO, INC."],"tldr":"Matrisome Bio is a Cambridge, Massachusetts start-up that aims treatments at the scaffolding around tumour cells, the extracellular matrix, rather than at the cells themselves. It is developing a radioactive medicine for lung cancer that has spread.","summary":"Matrisome Bio, Inc., of Cambridge, Massachusetts, describes itself as a seed-stage start-up delivering payloads to disease-associated components of the extracellular matrix of tumours and metastases, using a toolbox of nanobody-based binders. In fiscal year 2026 the National Cancer Institute funded its SBIR project on an extracellular matrix-targeted theranostic radiopharmaceutical for metastatic lung cancer (5R44CA298532-02, USD 1,013,647).","asOf":"2026-11-04","links":[{"label":"Official website","url":"https://matrisomebio.com/"},{"label":"NIH RePORTER: 5R44CA298532-02","url":"https://reporter.nih.gov/project-details/11419641"}],"tags":[],"related":[],"cancers":["lung-cancer"],"sections":["radiopharma"],"technologies":["radioligand-therapy"],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":["Read on matrisomebio.com and the NIH RePORTER record on 4 November 2026. The site names no product."],"hq":"Cambridge, MA","country":"US","companyType":"radiopharma","website":"https://matrisomebio.com/","stage":"startup","investors":[],"funding":[{"round":"Grant","year":2026,"amountUsd":1013647,"source":"https://reporter.nih.gov/project-details/11419641","note":"NCI SBIR (R44) award 5R44CA298532-02: Development of an extracellular matrix-targeted theranostic radiopharmaceutical for metastatic lung cancer"}]},"route":"/companies/matrisome-bio/","neighbours":{"cancer":[{"id":"lung-cancer","kind":"cancer","name":"Lung cancer (all types)","route":"/cancers/lung-cancer/"}],"section":[{"id":"radiopharma","kind":"section","name":"Radiopharmaceuticals & Theranostics","route":"/fronts/radiopharma/"}],"technology":[{"id":"radioligand-therapy","kind":"technology","name":"Radioligand therapy (beta emitters)","route":"/technologies/radioligand-therapy/"}]}}