{"entity":{"id":"menarini-silicon-biosystems","kind":"company","name":"Menarini Silicon Biosystems","aka":["Silicon Biosystems","CellSearch","DEPArray"],"tldr":"The Menarini group's diagnostics arm that owns CellSearch, the only regulator-cleared circulating tumour cell test, and DEPArray, an instrument that picks out single cells from a sample for sequencing.","summary":"Silicon Biosystems was founded in Bologna as a spin-out from the University of Bologna to commercialise DEPArray, a dielectrophoresis-based instrument that isolates individual cells from a mixed sample so they can be sequenced or analysed one at a time. The Menarini group acquired it in 2013 and in 2017 bought the CellSearch circulating tumour cell system from Janssen Diagnostics, uniting enumeration of circulating tumour cells with single-cell recovery. The company sells the instruments and reagents to hospital and research laboratories and runs a service laboratory in the United States; its main customers are pharmaceutical trials that use circulating tumour cell counts and single-cell analysis as biomarkers.","asOf":"2026-09-17","links":[{"label":"Official website","url":"https://www.siliconbiosystems.com"},{"label":"CellSearch","url":"https://www.cellsearchctc.com"}],"tags":[],"related":[],"cancers":["breast-cancer","prostate","colorectal"],"sections":[],"technologies":["cellsearch-ctc-count","ctc-capture","liquid-biopsy","single-cell-spatial"],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"hq":"Castel Maggiore (Bologna), Italy","country":"IT","companyType":"diagnostics","website":"https://www.siliconbiosystems.com","stage":"acquired","investors":[],"funding":[],"acquiredBy":"menarini"},"route":"/companies/menarini-silicon-biosystems/","neighbours":{"cancer":[{"id":"breast-cancer","kind":"cancer","name":"Breast cancer (all types)","route":"/cancers/breast-cancer/"},{"id":"colorectal","kind":"cancer","name":"Colorectal cancer","route":"/cancers/colorectal/"},{"id":"prostate","kind":"cancer","name":"Prostate cancer","route":"/cancers/prostate/"}],"technology":[{"id":"cellsearch-ctc-count","kind":"technology","name":"CellSearch circulating tumour cell count","route":"/technologies/cellsearch-ctc-count/"},{"id":"ctc-capture","kind":"technology","name":"Circulating tumour cell capture","route":"/technologies/ctc-capture/"},{"id":"liquid-biopsy","kind":"technology","name":"Liquid biopsy (ctDNA)","route":"/technologies/liquid-biopsy/"},{"id":"single-cell-spatial","kind":"technology","name":"Single-cell & spatial profiling","route":"/technologies/single-cell-spatial/"}],"company":[{"id":"menarini","kind":"company","name":"Menarini / Stemline","route":"/companies/menarini/"}]}}