{"entity":{"id":"michael-migden","kind":"person","name":"Michael R. Migden","aka":[],"tldr":"Houston dermatologist who led the trials that established cemiplimab, the first drug approved for advanced cutaneous squamous-cell carcinoma, and sonidegib for basal cell carcinoma.","summary":"Michael Migden is a dermatologist and Mohs surgeon at MD Anderson Cancer Center who runs trials of systemic therapy for non-melanoma skin cancer. He was first author of the 2018 New England Journal of Medicine report of cemiplimab in advanced cutaneous squamous-cell carcinoma (EMPOWER-CSCC 1 and its phase 1 expansion), which led to the first approval for this disease, and of the 2015 Lancet Oncology report of the BOLT trial of sonidegib in advanced basal cell carcinoma.","asOf":"2026-09-18","links":[],"tags":["skin","immunotherapy","trialist"],"related":[],"cancers":["advanced-cutaneous-scc","locally-advanced-bcc","skin-cancer"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":["md-anderson"],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":["paper-empower-cscc-1-cemiplimab-migden-nejm-2018","paper-bolt-sonidegib-migden-lancet-oncol-2015"],"journals":[],"dependsOn":[],"notes":[],"role":"Dermatologist and Mohs surgeon, MD Anderson Cancer Center","institutionId":"md-anderson","specialisms":["Cutaneous squamous-cell carcinoma","Basal cell carcinoma","Systemic therapy for skin cancer"],"profiles":[{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Migden%5BAuthor%5D"}],"papers":[]},"route":"/people/michael-migden/","neighbours":{"cancer":[{"id":"advanced-cutaneous-scc","kind":"cancer","name":"Advanced cutaneous squamous cell carcinoma","route":"/cancers/advanced-cutaneous-scc/"},{"id":"locally-advanced-bcc","kind":"cancer","name":"Locally advanced and metastatic basal cell carcinoma","route":"/cancers/locally-advanced-bcc/"},{"id":"skin-cancer","kind":"cancer","name":"Skin cancer (all types)","route":"/cancers/skin-cancer/"}],"institution":[{"id":"md-anderson","kind":"institution","name":"MD Anderson Cancer Center","route":"/institutions/md-anderson/"}],"paper":[{"id":"paper-bolt-sonidegib-migden-lancet-oncol-2015","kind":"paper","name":"BOLT: two doses of sonidegib in locally advanced or metastatic basal cell carcinoma","route":"/key-papers/paper-bolt-sonidegib-migden-lancet-oncol-2015/"},{"id":"paper-empower-cscc-1-cemiplimab-migden-nejm-2018","kind":"paper","name":"PD-1 blockade with cemiplimab in advanced cutaneous squamous cell carcinoma (EMPOWER-CSCC-1)","route":"/key-papers/paper-empower-cscc-1-cemiplimab-migden-nejm-2018/"}]}}