{"entity":{"id":"mimetas","kind":"company","name":"MIMETAS","aka":[],"tldr":"MIMETAS makes plates of tiny channels in which human cells grow with a flowing fluid supply, a small working model of tissue known as an organ-on-a-chip. Its cancer models let researchers watch whether immune cells, including CAR-T cells, can reach a tumour and kill it.","summary":"MIMETAS was founded in 2013 in Leiden, the Netherlands, and Gaithersburg, Maryland, by Paul Vulto and Jos Joore, who are co-chief executives, and has offices in the Netherlands, the United States and Japan. Its OrganoPlate, which the company calls the first mass-produced, quality-controlled organ-on-a-chip platform, holds perfused 3D human tissue models. Its oncology models are 3D tumour models in a perfused system that include infiltrating lymphocytes; the company describes uses in modelling T-cell trafficking into tumours for T-cell engagers, CAR-T extravasation, migration and tumour killing, immune suppression in co-cultures with M2 macrophages and fibroblasts, a 1,537-compound screen in an angiogenic sprouting model, and combination therapy screening in hepatocellular carcinoma.","asOf":"2026-11-03","links":[{"label":"Official website","url":"https://www.mimetas.com/"},{"label":"Company (founded 2013)","url":"https://www.mimetas.com/company"},{"label":"Oncology models","url":"https://www.mimetas.com/oncology"}],"tags":[],"related":[],"cancers":["hcc"],"sections":["drug-discovery"],"technologies":["tumour-on-chip","immune-tumour-coculture-models"],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":["Ownership and financing are not stated on the pages read. Headquarters is given as Leiden, one of the two founding sites; the company does not name a headquarters. companyType cro-services is the corpus's nearest category for a platform and model-services provider."],"hq":"Leiden","country":"NL","companyType":"cro-services","website":"https://www.mimetas.com/","founded":2013,"investors":[],"funding":[]},"route":"/companies/mimetas/","neighbours":{"cancer":[{"id":"hcc","kind":"cancer","name":"Hepatocellular carcinoma","route":"/cancers/hcc/"}],"section":[{"id":"drug-discovery","kind":"section","name":"Drug Discovery Platforms","route":"/fronts/drug-discovery/"}],"technology":[{"id":"immune-tumour-coculture-models","kind":"technology","name":"Immune-tumour co-culture models","route":"/technologies/immune-tumour-coculture-models/"},{"id":"tumour-on-chip","kind":"technology","name":"Tumour-on-a-chip","route":"/technologies/tumour-on-chip/"}]}}