{"entity":{"id":"moleculin","kind":"company","name":"Moleculin Biotech","aka":["Moleculin Biotech, Inc.","Moleculin"],"tldr":"Moleculin is a Houston biotech whose annamycin, an anthracycline designed to spare the heart, is in a phase 3 trial with cytarabine for relapsed acute myeloid leukaemia.","summary":"Moleculin Biotech, headquartered in Houston, Texas, licenses drug candidates from MD Anderson Cancer Center. Its lead, annamycin, is a liposomal anthracycline engineered to avoid the cardiotoxicity of doxorubicin and to evade multidrug resistance pumps, and is in the phase 3 MIRACLE trial with cytarabine in relapsed or refractory acute myeloid leukaemia; WP1066, a STAT3 inhibitor, is in earlier trials in brain tumours. Its trials are registered on ClinicalTrials.gov under Moleculin as lead sponsor.","asOf":"2026-09-11","links":[{"label":"Official website","url":"https://www.moleculin.com"},{"label":"ClinicalTrials.gov: trials led by Moleculin Biotech, Inc.","url":"https://clinicaltrials.gov/search?lead=Moleculin%20Biotech%2C%20Inc."}],"tags":["ctgov-sponsor"],"related":[],"cancers":["aml","glioblastoma"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":["md-anderson"],"pathways":[],"terms":["pivotal-trial","clinical-trial"],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"notes":[],"provenance":{"editedBy":"OnCo ingestion (ClinicalTrials.gov v2 + sponsor websites)","editedOn":"2026-09-11"},"hq":"Houston, TX","country":"US","companyType":"biotech","website":"https://www.moleculin.com","stage":"public","investors":[],"funding":[]},"route":"/companies/moleculin/","neighbours":{"cancer":[{"id":"aml","kind":"cancer","name":"Acute myeloid leukaemia","route":"/cancers/aml/"},{"id":"glioblastoma","kind":"cancer","name":"Glioma & glioblastoma","route":"/cancers/glioblastoma/"}],"institution":[{"id":"md-anderson","kind":"institution","name":"MD Anderson Cancer Center","route":"/institutions/md-anderson/"}],"term":[{"id":"clinical-trial","kind":"term","name":"Clinical trial","route":"/terms/clinical-trial/"},{"id":"pivotal-trial","kind":"term","name":"Pivotal (registrational) trial","route":"/terms/pivotal-trial/"}]}}