{"entity":{"id":"nct00002719","kind":"trial","name":"Combination Chemotherapy With or Without G-CSF in Treating Older Patients With Acute Myeloid Leukemia","aka":[],"tldr":"A phase 3 trial of Filgrastim, Amsacrine, Carmustine, Cytarabine, Etoposide, Idarubicin and Mitoxantrone in Leukaemia, run by European Organisation for Research and Treatment of Cancer - EORTC, completed.","summary":"Combination Chemotherapy With or Without G-CSF in Treating Older Patients With Acute Myeloid Leukemia is a phase 3 interventional study registered as NCT00002719 by European Organisation for Research and Treatment of Cancer - EORTC, with 500 participants recorded, started 1995-12 and reaching its primary completion in 2001-11. Interventions recorded: filgrastim, amsacrine, carmustine, cytarabine, etoposide, idarubicin, mitoxantrone hydrochloride, peripheral blood stem cell transplantation. Conditions recorded: Leukemia, Neutropenia.\n\nLinked to the drug Amsacrine because the registry names it among its interventions and Leukaemia among its conditions. Registry record only: no result has been read by an editor.","status":"completed","asOf":"2026-09-22","links":[{"label":"ClinicalTrials.gov NCT00002719","url":"https://clinicaltrials.gov/study/NCT00002719"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["leukaemia"],"sections":[],"technologies":[],"targets":[],"drugs":["filgrastim","amsacrine","carmustine","cytarabine","etoposide","idarubicin","mitoxantrone"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT00002719","phase":"3","setting":"RANDOMIZED PHASE III STUDY TO EVALUATE THE VALUE OF rHuG-CSF IN INDUCTION AND OF AN ORAL SCHEDULE AS CONSOLIDATION TREATMENT IN ELDERLY PATIENTS WITH ACUTE MYELOGENOUS LEUMEKIA (AML-13 PROTOCOL)","sponsor":"European Organisation for Research and Treatment of Cancer - EORTC","enrolled":500,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct00002719/","neighbours":{"cancer":[{"id":"leukaemia","kind":"cancer","name":"Leukaemia (all types)","route":"/cancers/leukaemia/"}],"drug":[{"id":"amsacrine","kind":"drug","name":"Amsacrine","route":"/drugs/amsacrine/"},{"id":"carmustine","kind":"drug","name":"Carmustine","route":"/drugs/carmustine/"},{"id":"cytarabine","kind":"drug","name":"Cytarabine","route":"/drugs/cytarabine/"},{"id":"etoposide","kind":"drug","name":"Etoposide","route":"/drugs/etoposide/"},{"id":"filgrastim","kind":"drug","name":"Filgrastim (G-CSF)","route":"/drugs/filgrastim/"},{"id":"idarubicin","kind":"drug","name":"Idarubicin","route":"/drugs/idarubicin/"},{"id":"mitoxantrone","kind":"drug","name":"Mitoxantrone","route":"/drugs/mitoxantrone/"}]}}