{"entity":{"id":"nct00070564","kind":"trial","name":"SWOG S0221 adjuvant chemotherapy schedules","aka":["S0221 Adjuvant Doxorubicin, Cyclophosphamide, and Paclitaxel in Treating Patients With Breast Cancer"],"tldr":"S0221 compares schedules for chemotherapy after breast surgery. It studies which schedule controls cancer while tracking side effects.","summary":"S0221 compares schedules for chemotherapy after breast surgery. It studies which schedule controls cancer while tracking side effects.\n\nInterventional study registered as NCT00070564, sponsored by SWOG Cancer Research Network. Registry phase: 3. Registry enrollment is 3,294 participants (actual). Registry status checked October 10, 2026: active not recruiting. UCSF lists this study as closed to local enrollment; local availability and overall registry status are separate. See the registry for full eligibility and current sites.","status":"active","asOf":"2026-10-10","links":[{"label":"ClinicalTrials.gov NCT00070564","url":"https://clinicaltrials.gov/study/NCT00070564"},{"label":"UCSF study listing and local availability","url":"https://clinicaltrials.ucsf.edu/trial/NCT00070564"}],"tags":["ucsf-breast-coverage","interventional"],"related":[],"cancers":["breast-cancer"],"sections":[],"technologies":[],"targets":[],"drugs":["cyclophosphamide","doxorubicin","paclitaxel","pegfilgrastim"],"companies":[],"institutions":["ucsf"],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT00070564","phase":"3","setting":"Resected stage I to III breast cancer","sponsor":"SWOG Cancer Research Network","participation":[{"nct":"NCT00070564","source":"https://clinicaltrials.gov/study/NCT00070564","fetchedAt":"2026-10-10T20:54:22.519717Z","studySha256":"ccd3f8d8cd7a052aea44f22820cf55c141c076459794767083e3b85af6f15698","overallStatus":"ACTIVE_NOT_RECRUITING","lastUpdatePosted":"2026-08-28","leadSponsor":"SWOG Cancer Research Network","collaboratorCount":1,"minimumAge":"18 Years","sex":"ALL","healthyVolunteers":false,"hasEligibility":true,"enrolment":3294,"enrolmentType":"ACTUAL","siteCount":542,"recruitingSiteCount":0,"countries":["Canada","Puerto Rico","United States"]}],"started":"2003-11","enrolled":3294,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct00070564/","neighbours":{"cancer":[{"id":"breast-cancer","kind":"cancer","name":"Breast cancer (all types)","route":"/cancers/breast-cancer/"}],"drug":[{"id":"cyclophosphamide","kind":"drug","name":"Cyclophosphamide","route":"/drugs/cyclophosphamide/"},{"id":"doxorubicin","kind":"drug","name":"Doxorubicin","route":"/drugs/doxorubicin/"},{"id":"paclitaxel","kind":"drug","name":"Paclitaxel / nab-paclitaxel","route":"/drugs/paclitaxel/"},{"id":"pegfilgrastim","kind":"drug","name":"Pegfilgrastim","route":"/drugs/pegfilgrastim/"}],"institution":[{"id":"ucsf","kind":"institution","name":"UCSF Helen Diller Family Comprehensive Cancer Center","route":"/institutions/ucsf/"}]}}