{"entity":{"id":"nct00101582","kind":"trial","name":"Palifermin for the Reduction of Oral Mucositis in Patients With Locally Advanced Head and Neck Cancer","aka":[],"tldr":"A phase 3 trial of Palifermin in Head and neck squamous cell carcinoma, run by Swedish Orphan Biovitrum, completed.","summary":"Palifermin for the Reduction of Oral Mucositis in Patients With Locally Advanced Head and Neck Cancer is a phase 3 interventional study registered as NCT00101582 by Swedish Orphan Biovitrum, with 188 participants recorded, started 2005-08 and reaching its primary completion in 2007-09. Interventions recorded: Placebo, palifermin, cisplatin chemotherapy, Radiotherapy. Conditions recorded: Mucositis, Solid Tumors, Stomatitis, Head and Neck Cancer, Squamous Cell Carcinoma.\n\nLinked to the drug Palifermin because the registry names it among its interventions and Head and neck squamous cell carcinoma among its conditions. Registry record only: no result has been read by an editor.","status":"completed","asOf":"2026-09-22","links":[{"label":"ClinicalTrials.gov NCT00101582","url":"https://clinicaltrials.gov/study/NCT00101582"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["head-and-neck"],"sections":[],"technologies":[],"targets":[],"drugs":["palifermin"],"companies":["sobi"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT00101582","phase":"3","setting":"Phase 3, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Weekly Doses of Palifermin (rHuKGF) for the Reduction of Oral Mucositis in Subjects With Advanced Head and Neck Cancer Receiving Radiotherapy With Concurrent Chemotherapy (RT/CT)","sponsor":"Swedish Orphan Biovitrum","enrolled":188,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct00101582/","neighbours":{"cancer":[{"id":"head-and-neck","kind":"cancer","name":"Head and neck squamous cell carcinoma","route":"/cancers/head-and-neck/"}],"drug":[{"id":"palifermin","kind":"drug","name":"Palifermin","route":"/drugs/palifermin/"}],"company":[{"id":"sobi","kind":"company","name":"Sobi (Swedish Orphan Biovitrum)","route":"/companies/sobi/"}]}}