{"entity":{"id":"nct00109031","kind":"trial","name":"Palifermin for the Reduction of Oral Mucositis in Single-dose Evaluation (PROMISE)","aka":[],"tldr":"A phase 3 trial of Palifermin, Cyclophosphamide and Etoposide in Leukaemia, run by Swedish Orphan Biovitrum, completed.","summary":"Palifermin for the Reduction of Oral Mucositis in Single-dose Evaluation (PROMISE) is a phase 3 interventional study registered as NCT00109031 by Swedish Orphan Biovitrum, with 47 participants recorded, started 2005-01 and reaching its primary completion in 2006-02. Interventions recorded: palifermin, Total Body Irradiation, Cyclophosphamide, Etoposide, Placebo. Conditions recorded: Cancer, Lymphoma, Leukemia.\n\nLinked to the drug Palifermin because the registry names it among its interventions and Leukaemia among its conditions. Registry record only: no result has been read by an editor.","status":"completed","asOf":"2026-09-22","links":[{"label":"ClinicalTrials.gov NCT00109031","url":"https://clinicaltrials.gov/study/NCT00109031"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["leukaemia"],"sections":[],"technologies":[],"targets":[],"drugs":["palifermin","cyclophosphamide","etoposide"],"companies":["sobi"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT00109031","phase":"3","setting":"A Randomized, Blinded, Active-control Trial of Palifermin (rHuKGF) to Evaluate Oral Mucositis in Subjects With Hematologic Malignancies Undergoing Fractionated Total Body Irradiation (fTBI) and High Dose Chemotherapy With Autologous Peripheral Blood Progenitor Cell (PBPC) Transplantation","sponsor":"Swedish Orphan Biovitrum","enrolled":47,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct00109031/","neighbours":{"cancer":[{"id":"leukaemia","kind":"cancer","name":"Leukaemia (all types)","route":"/cancers/leukaemia/"}],"drug":[{"id":"cyclophosphamide","kind":"drug","name":"Cyclophosphamide","route":"/drugs/cyclophosphamide/"},{"id":"etoposide","kind":"drug","name":"Etoposide","route":"/drugs/etoposide/"},{"id":"palifermin","kind":"drug","name":"Palifermin","route":"/drugs/palifermin/"}],"company":[{"id":"sobi","kind":"company","name":"Sobi (Swedish Orphan Biovitrum)","route":"/companies/sobi/"}]}}