{"entity":{"id":"nct00254163","kind":"trial","name":"Fludarabine, Cyclophosphamide, and Rituximab Versus Pentostatin, Cyclophosphamide, and Rituximab in Previously Untreated or Treated B-Cell Chronic Lymphocytic Leukemia Patients","aka":[],"tldr":"A phase 3 trial of Fludarabine, Cyclophosphamide, Rituximab and Pentostatin in Chronic lymphocytic leukaemia, run by US Oncology Research, completed.","summary":"Fludarabine, Cyclophosphamide, and Rituximab Versus Pentostatin, Cyclophosphamide, and Rituximab in Previously Untreated or Treated B-Cell Chronic Lymphocytic Leukemia Patients is a phase 3 interventional study registered as NCT00254163 by US Oncology Research, with 184 participants recorded, started 2003-12 and reaching its primary completion in 2011-09. Interventions recorded: Fludarabine, Cyclophosphamide, Rituximab, Pentostatin. Conditions recorded: B-Cell Chronic Lymphocytic Leukemia.\n\nLinked to the drug Pentostatin because the registry names it among its interventions and Chronic lymphocytic leukaemia among its conditions. Registry record only: no result has been read by an editor.","status":"completed","asOf":"2026-09-22","links":[{"label":"ClinicalTrials.gov NCT00254163","url":"https://clinicaltrials.gov/study/NCT00254163"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["cll"],"sections":[],"technologies":[],"targets":[],"drugs":["fludarabine","cyclophosphamide","rituximab","pentostatin"],"companies":["mckesson-us-oncology"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT00254163","phase":"3","setting":"A Prospective, Randomized, Open Label, Phase III Trial of Fludarabine, Cyclophosphamide, and Rituximab vs. Pentostatin, Cyclophosphamide, and Rituximab in Previously Untreated or Treated B-cell Chronic Lymphocytic Leukemia","sponsor":"US Oncology Research","enrolled":184,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct00254163/","neighbours":{"cancer":[{"id":"cll","kind":"cancer","name":"Chronic lymphocytic leukaemia","route":"/cancers/cll/"}],"drug":[{"id":"cyclophosphamide","kind":"drug","name":"Cyclophosphamide","route":"/drugs/cyclophosphamide/"},{"id":"fludarabine","kind":"drug","name":"Fludarabine","route":"/drugs/fludarabine/"},{"id":"pentostatin","kind":"drug","name":"Pentostatin","route":"/drugs/pentostatin/"},{"id":"rituximab","kind":"drug","name":"Rituximab","route":"/drugs/rituximab/"}],"company":[{"id":"mckesson-us-oncology","kind":"company","name":"McKesson / The US Oncology Network","route":"/companies/mckesson-us-oncology/"}]}}