{"entity":{"id":"nct00628810","kind":"trial","name":"Combination Chemotherapy and Bevacizumab in Treating Patients With Metastatic Colorectal Cancer","aka":[],"tldr":"A phase 2 trial of UGT1A1 genotyping before irinotecan in Colorectal cancer, run by Federation Francophone de Cancerologie Digestive, completed.","summary":"Combination Chemotherapy and Bevacizumab in Treating Patients With Metastatic Colorectal Cancer is a phase 2 interventional study registered as NCT00628810 by Federation Francophone de Cancerologie Digestive, with 86 participants recorded, started 2007-01 and reaching its primary completion in 2008-01. Interventions recorded: bevacizumab, fluorouracil, irinotecan hydrochloride, leucovorin calcium. Conditions recorded: Colorectal Cancer.\n\nLinked to the technology UGT1A1 genotyping before irinotecan because the registry's title names it (\"ugt1a1 28\") and Colorectal cancer among its conditions. Registry record only: no result has been read by an editor.","status":"completed","asOf":"2026-09-22","links":[{"label":"ClinicalTrials.gov NCT00628810","url":"https://clinicaltrials.gov/study/NCT00628810"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["colorectal"],"sections":[],"technologies":["ugt1a1-genotyping"],"targets":[],"drugs":["fluorouracil","irinotecan","leucovorin"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT00628810","phase":"2","setting":"Chemotherapy With FOLFIRI Plus Bevacizumab (AvastinR) in Patients With Metastatic Colorectal Cancer Bearing Genotype UGT1A1*1/UGT1A1*1 or UGT1A1*1/UGT1A1*1/UGT1A1*28: Prospective, Phase II, Multicenter Study","sponsor":"Federation Francophone de Cancerologie Digestive","enrolled":86,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct00628810/","neighbours":{"cancer":[{"id":"colorectal","kind":"cancer","name":"Colorectal cancer","route":"/cancers/colorectal/"}],"technology":[{"id":"ugt1a1-genotyping","kind":"technology","name":"UGT1A1 genotyping before irinotecan","route":"/technologies/ugt1a1-genotyping/"}],"drug":[{"id":"fluorouracil","kind":"drug","name":"Fluorouracil (5-FU)","route":"/drugs/fluorouracil/"},{"id":"irinotecan","kind":"drug","name":"Irinotecan (and liposomal irinotecan)","route":"/drugs/irinotecan/"},{"id":"leucovorin","kind":"drug","name":"Leucovorin (folinic acid)","route":"/drugs/leucovorin/"}]}}