{"entity":{"id":"nct00634322","kind":"trial","name":"High Dose Methotrexate With Leucovorin Rescue With or Without Glucarpidase in Osteosarcoma","aka":[],"tldr":"A phase 2 trial of Glucarpidase and Leucovorin in Osteosarcoma, run by BTG International Inc., recorded as terminated on the registry.","summary":"High Dose Methotrexate With Leucovorin Rescue With or Without Glucarpidase in Osteosarcoma is a phase 2 interventional study registered as NCT00634322 by BTG International Inc., with 7 participants recorded, started 2008-10 and due to reach its primary completion in 2009-03. Interventions recorded: glucarpidase, leucovorin. Conditions recorded: Osteosarcoma.\n\nLinked to the drug Glucarpidase because the registry names it among its interventions and Osteosarcoma among its conditions. Registry record only: no result has been read by an editor.","asOf":"2026-09-22","links":[{"label":"ClinicalTrials.gov NCT00634322","url":"https://clinicaltrials.gov/study/NCT00634322"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["osteosarcoma"],"sections":[],"technologies":[],"targets":[],"drugs":["glucarpidase","leucovorin"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT00634322","phase":"2","setting":"Randomized, Blinded, Placebo-Controlled Trial of High Dose Methotrexate With Leucovorin Rescue (HDMTX-LV) With or Without Glucarpidase in Osteosarcoma","sponsor":"BTG International Inc.","enrolled":7,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct00634322/","neighbours":{"cancer":[{"id":"osteosarcoma","kind":"cancer","name":"Osteosarcoma","route":"/cancers/osteosarcoma/"}],"drug":[{"id":"glucarpidase","kind":"drug","name":"Glucarpidase","route":"/drugs/glucarpidase/"},{"id":"leucovorin","kind":"drug","name":"Leucovorin (folinic acid)","route":"/drugs/leucovorin/"}]}}