{"entity":{"id":"nct00660894","kind":"trial","name":"Tegafur-Uracil and Leucovorin or S-1 in Treating Patients With Stage III Colon Cancer That Has Been Completely Removed by Surgery","aka":[],"tldr":"A phase 3 trial of Leucovorin and Tegafur, gimeracil and oteracil in Colorectal cancer, run by Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan, completed.","summary":"Tegafur-Uracil and Leucovorin or S-1 in Treating Patients With Stage III Colon Cancer That Has Been Completely Removed by Surgery is a phase 3 interventional study registered as NCT00660894 by Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan, with 1535 participants recorded, started 2008-04 and reaching its primary completion in 2012-06. Interventions recorded: folinate calcium, tegafur-uracil, tegafur-gimeracil-oteracil potassium. Conditions recorded: Colorectal Cancer.\n\nLinked to the drug Tegafur, gimeracil and oteracil because the registry names it among its interventions and Colorectal cancer among its conditions. Registry record only: no result has been read by an editor.","status":"completed","asOf":"2026-09-22","links":[{"label":"ClinicalTrials.gov NCT00660894","url":"https://clinicaltrials.gov/study/NCT00660894"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["colorectal"],"sections":[],"technologies":[],"targets":[],"drugs":["leucovorin","tegafur-gimeracil-oteracil"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT00660894","phase":"3","setting":"Randomized Phase III Study of UFT+Leucovorin vs. TS-1 as Adjuvant Treatment for Stage III Colon Cancer, and Investigate Predictive Factors Based on Gene Expression","sponsor":"Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan","enrolled":1535,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct00660894/","neighbours":{"cancer":[{"id":"colorectal","kind":"cancer","name":"Colorectal cancer","route":"/cancers/colorectal/"}],"drug":[{"id":"leucovorin","kind":"drug","name":"Leucovorin (folinic acid)","route":"/drugs/leucovorin/"},{"id":"tegafur-gimeracil-oteracil","kind":"drug","name":"Tegafur, gimeracil and oteracil (S-1)","route":"/drugs/tegafur-gimeracil-oteracil/"}]}}