{"entity":{"id":"nct00822393","kind":"trial","name":"Clinical Phase III Trial Treosulfan-based Conditioning Versus Reduced-intensity Conditioning (RIC)","aka":[],"tldr":"A phase 3 trial of Busulfan and Treosulfan in Acute myeloid leukaemia, run by medac GmbH, completed.","summary":"Clinical Phase III Trial Treosulfan-based Conditioning Versus Reduced-intensity Conditioning (RIC) is a phase 3 interventional study registered as NCT00822393 by medac GmbH, with 570 participants recorded, started 2008-11-24 and reaching its primary completion in 2018-01-25. Interventions recorded: Busulfan, Treosulfan. Conditions recorded: Acute Myeloid Leukemia, Myelodysplastic Syndrome.\n\nLinked to the drug Treosulfan because the registry names it among its interventions and Acute myeloid leukaemia among its conditions. Registry record only: no result has been read by an editor.","status":"completed","asOf":"2026-09-22","links":[{"label":"ClinicalTrials.gov NCT00822393","url":"https://clinicaltrials.gov/study/NCT00822393"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["aml"],"sections":[],"technologies":[],"targets":[],"drugs":["busulfan","treosulfan"],"companies":["medac"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT00822393","phase":"3","setting":"Clinical Phase III Trial to Compare Treosulfan-based Conditioning Therapy With Busulfan-based Reduced-intensity Conditioning (RIC) Prior to Allogeneic Haematopoietic Stem Cell Transplantation in Patients With AML or MDS Considered Ineligible to Standard Conditioning Regimens","sponsor":"medac GmbH","enrolled":570,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct00822393/","neighbours":{"cancer":[{"id":"aml","kind":"cancer","name":"Acute myeloid leukaemia","route":"/cancers/aml/"}],"drug":[{"id":"busulfan","kind":"drug","name":"Busulfan","route":"/drugs/busulfan/"},{"id":"treosulfan","kind":"drug","name":"Treosulfan","route":"/drugs/treosulfan/"}],"company":[{"id":"medac","kind":"company","name":"medac","route":"/companies/medac/"}]}}