{"entity":{"id":"nct01828099","kind":"trial","name":"LDK378 Versus Chemotherapy in Previously Untreated Patients With ALK Rearranged Non-small Cell Lung Cancer","aka":[],"tldr":"A phase 3 trial of Ceritinib, Pemetrexed, Cisplatin and Carboplatin in Non-small-cell lung cancer, run by Novartis Pharmaceuticals, completed.","summary":"LDK378 Versus Chemotherapy in Previously Untreated Patients With ALK Rearranged Non-small Cell Lung Cancer is a phase 3 interventional study registered as NCT01828099 by Novartis Pharmaceuticals, with 376 participants recorded, started 2013-07-09 and reaching its primary completion in 2016-06-24. Interventions recorded: Ceritinib, Pemetrexed, Cisplatin, Carboplatin. Conditions recorded: Non-Small Cell Lung Cancer.\n\nLinked to the drug Ceritinib because the registry names it among its interventions and Non-small-cell lung cancer among its conditions. Registry record only: no result has been read by an editor.","status":"completed","asOf":"2026-09-22","links":[{"label":"ClinicalTrials.gov NCT01828099","url":"https://clinicaltrials.gov/study/NCT01828099"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["nsclc"],"sections":[],"technologies":[],"targets":[],"drugs":["ceritinib","pemetrexed","cisplatin","carboplatin"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT01828099","phase":"3","setting":"A Phase III Multicenter, Randomized Study of Oral LDK378 Versus Standard Chemotherapy in Previously Untreated Adult Patients With ALK Rearranged (ALK-positive), Stage IIIB or IV, Non-squamous Non-small Cell Lung Cancer","sponsor":"Novartis Pharmaceuticals","enrolled":376,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct01828099/","neighbours":{"cancer":[{"id":"nsclc","kind":"cancer","name":"Non-small-cell lung cancer","route":"/cancers/nsclc/"}],"drug":[{"id":"carboplatin","kind":"drug","name":"Carboplatin","route":"/drugs/carboplatin/"},{"id":"ceritinib","kind":"drug","name":"Ceritinib","route":"/drugs/ceritinib/"},{"id":"cisplatin","kind":"drug","name":"Cisplatin","route":"/drugs/cisplatin/"},{"id":"pemetrexed","kind":"drug","name":"Pemetrexed","route":"/drugs/pemetrexed/"}]}}