{"entity":{"id":"nct02572141","kind":"trial","name":"FOLFOX or CAPOX Perioperative Chemotherapy Versus Postoperative Chemotherapy for Locally Advanced Colon Cancer (OPTICAL)","aka":["OPTICAL"],"tldr":"A phase 3 trial in colorectal cancer, run by Sun Yat-sen University, active but no longer recruiting.","summary":"FOLFOX or CAPOX Perioperative Chemotherapy Versus Postoperative Chemotherapy for Locally Advanced Colon Cancer (OPTICAL) is a phase 3, randomised interventional study registered as NCT02572141 by Sun Yat-sen University, with a registry enrolment figure of 738 participants, started 2015-01-01 and due to reach its primary completion in 2023-03-15. Interventions recorded: Perioperative chemotherapy with mFOLFOX6 or CAPOX regimens; Postoperative chemotherapy with mFOLFOX6 or CAPOX regimens. Conditions listed: Colon Cancer. Primary outcome: Disease-free survival. Colorectal eligibility wording from the registry: \"Histological or cytological documentation of adenocarcinoma of the colon (≥ 15 cm from the anal verge)\". Sites: China. No results are recorded here; the registry entry is the source.","status":"active","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT02572141","url":"https://clinicaltrials.gov/study/NCT02572141"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["colon-cancer"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT02572141","phase":"3","setting":"A Phase III Study to Evaluate the 3-year Disease-free Survival in Patients With Locally Advanced Colon Cancer Receiving Either Perioperative or Postoperative Chemotherapy With FOLFOX or CAPOX Regimens","sponsor":"Sun Yat-sen University","enrolled":738,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct02572141/","neighbours":{"cancer":[{"id":"colon-cancer","kind":"cancer","name":"Colon cancer (adenocarcinoma of the colon)","route":"/cancers/colon-cancer/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}