{"entity":{"id":"nct02628067","kind":"trial","name":"Study of Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-3475-158/KEYNOTE-158)","aka":[],"tldr":"A phase 2 trial of Pembrolizumab in metastatic cancer and biliary tract cancer, run by Merck Sharp & Dohme LLC, active and no longer recruiting.","summary":"Study of Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-3475-158/KEYNOTE-158) is a phase 2 interventional study registered as NCT02628067 by Merck Sharp & Dohme LLC, with 1609 participants planned, started 2015-12-18 and due to reach its primary completion in 2027-05-04. Interventions recorded: pembrolizumab, pembrolizumab. Conditions listed: Advanced Cancer, Anal Carcinoma, Anal Cancer, Biliary Cancer. No results are recorded here; the registry entry is the source.","status":"active","asOf":"2026-09-16","links":[{"label":"ClinicalTrials.gov NCT02628067","url":"https://clinicaltrials.gov/study/NCT02628067"}],"tags":["ctgov-ingest"],"related":[],"cancers":["metastatic-cancer","cholangiocarcinoma","endometrial","cervical","vulvar"],"sections":[],"technologies":[],"targets":[],"drugs":["pembrolizumab"],"companies":["merck"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"notes":[],"nct":"NCT02628067","phase":"2","setting":"A Clinical Trial of Pembrolizumab (MK-3475) Evaluating Predictive Biomarkers in Subjects With Advanced Solid Tumors (KEYNOTE 158)","sponsor":"Merck Sharp & Dohme LLC","enrolled":1609,"outcomes":[]},"route":"/trials/nct02628067/","neighbours":{"cancer":[{"id":"cholangiocarcinoma","kind":"cancer","name":"Biliary tract cancer (cholangiocarcinoma)","route":"/cancers/cholangiocarcinoma/"},{"id":"cervical","kind":"cancer","name":"Cervical cancer","route":"/cancers/cervical/"},{"id":"endometrial","kind":"cancer","name":"Endometrial cancer","route":"/cancers/endometrial/"},{"id":"metastatic-cancer","kind":"cancer","name":"Metastatic cancer (cancer that has spread)","route":"/cancers/metastatic-cancer/"},{"id":"vulvar","kind":"cancer","name":"Vulvar cancer","route":"/cancers/vulvar/"}],"drug":[{"id":"pembrolizumab","kind":"drug","name":"Pembrolizumab","route":"/drugs/pembrolizumab/"}],"company":[{"id":"merck","kind":"company","name":"Merck & Co. (MSD)","route":"/companies/merck/"}]}}