{"entity":{"id":"nct03187288","kind":"trial","name":"Study of CFI-400945 Fumarate in Patients With Relapsed or Refractory AML or MDS","aka":[],"tldr":"A phase 1 trial of CFI-400945 run by University Health Network, Toronto, completed.","summary":"Study of CFI-400945 Fumarate in Patients With Relapsed or Refractory AML or MDS is a phase 1 interventional study registered as NCT03187288 by University Health Network, Toronto, with 13 participants enrolled, started 2018-05-25. Conditions recorded: Acute Myeloid Leukemia, Myelodysplastic Syndromes, Relapsed Cancer and Refractory Cancer. Interventions recorded: CFI-400945 Fumarate.","status":"completed","asOf":"2026-11-03","links":[{"label":"ClinicalTrials.gov NCT03187288","url":"https://clinicaltrials.gov/study/NCT03187288"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["aml","mds","metastatic-cancer"],"sections":[],"technologies":[],"targets":[],"drugs":["cfi-400945"],"companies":["treadwell-therapeutics"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT03187288","phase":"1","setting":"An Open-Label, Dose Escalation, Safety and Pharmacokinetic Study of CFI-400945 Fumarate Administered Orally to Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome","sponsor":"University Health Network, Toronto","enrolled":13,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct03187288/","neighbours":{"cancer":[{"id":"aml","kind":"cancer","name":"Acute myeloid leukaemia","route":"/cancers/aml/"},{"id":"metastatic-cancer","kind":"cancer","name":"Metastatic cancer (cancer that has spread)","route":"/cancers/metastatic-cancer/"},{"id":"mds","kind":"cancer","name":"Myelodysplastic syndromes / neoplasms (MDS)","route":"/cancers/mds/"}],"drug":[{"id":"cfi-400945","kind":"drug","name":"CFI-400945","route":"/drugs/cfi-400945/"}],"company":[{"id":"treadwell-therapeutics","kind":"company","name":"Treadwell Therapeutics","route":"/companies/treadwell-therapeutics/"}]}}