{"entity":{"id":"nct03206671","kind":"trial","name":"Treatment Protocol of the NHL-BFM and the NOPHO Study Groups for Mature Aggressive B-cell Lymphoma and Leukemia in Children and Adolescents","aka":[],"tldr":"A phase 3 trial of Cyclophosphamide, Cytarabine, Dexamethasone, Doxorubicin, Vindesine, Etoposide, Ifosfamide, Methotrexate, Prednisone and Vincristine in Non-Hodgkin lymphoma, run by University Hospital Muenster, active and no longer recruiting.","summary":"Treatment Protocol of the NHL-BFM and the NOPHO Study Groups for Mature Aggressive B-cell Lymphoma and Leukemia in Children and Adolescents is a phase 3 interventional study registered as NCT03206671 by University Hospital Muenster, with 650 participants planned, started 2017-08-03 and due to reach its primary completion in 2027-06. Interventions recorded: Rituximab window, Additional doses of Rituximab, Cyclophosphamide, Cytarabine, Dexamethasone, Doxorubicin hydrochloride, Vindesine Sulfate, Etoposide, Ifosfamide, Methotrexate, Prednisolone, Vincristine. Conditions recorded: Mature B-cell Non-Hodgkin Lymphoma.\n\nLinked to the drug Vindesine because the registry names it among its interventions and Non-Hodgkin lymphoma among its conditions. Registry record only: no result has been read by an editor.","status":"active","asOf":"2026-09-22","links":[{"label":"ClinicalTrials.gov NCT03206671","url":"https://clinicaltrials.gov/study/NCT03206671"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["non-hodgkin-lymphoma"],"sections":[],"technologies":[],"targets":[],"drugs":["cyclophosphamide","cytarabine","dexamethasone","doxorubicin","vindesine","etoposide","ifosfamide","methotrexate","prednisone","vincristine"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT03206671","phase":"3","setting":"B-NHL 2013 - Treatment Protocol of the NHL-BFM and the NOPHO Study Groups for Mature Aggressive B-cell Lymphoma and Leukemia in Children and Adolescents","sponsor":"University Hospital Muenster","enrolled":650,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct03206671/","neighbours":{"cancer":[{"id":"non-hodgkin-lymphoma","kind":"cancer","name":"Non-Hodgkin lymphoma (all types)","route":"/cancers/non-hodgkin-lymphoma/"}],"drug":[{"id":"cyclophosphamide","kind":"drug","name":"Cyclophosphamide","route":"/drugs/cyclophosphamide/"},{"id":"cytarabine","kind":"drug","name":"Cytarabine","route":"/drugs/cytarabine/"},{"id":"dexamethasone","kind":"drug","name":"Dexamethasone","route":"/drugs/dexamethasone/"},{"id":"doxorubicin","kind":"drug","name":"Doxorubicin","route":"/drugs/doxorubicin/"},{"id":"etoposide","kind":"drug","name":"Etoposide","route":"/drugs/etoposide/"},{"id":"ifosfamide","kind":"drug","name":"Ifosfamide","route":"/drugs/ifosfamide/"},{"id":"methotrexate","kind":"drug","name":"Methotrexate","route":"/drugs/methotrexate/"},{"id":"prednisone","kind":"drug","name":"Prednisone","route":"/drugs/prednisone/"},{"id":"vincristine","kind":"drug","name":"Vincristine","route":"/drugs/vincristine/"},{"id":"vindesine","kind":"drug","name":"Vindesine","route":"/drugs/vindesine/"}]}}