{"entity":{"id":"nct03301168","kind":"trial","name":"Study of Gene Modified Donor T-cells Following TCR Alpha Beta Positive Depleted Stem Cell Transplant","aka":[],"tldr":"A phase 1/2 trial of BPX-501 T cells in acute lymphoblastic leukaemia, acute myeloid leukaemia, non-Hodgkin lymphoma and myelodysplastic syndromes / neoplasms, run by Bellicum Pharmaceuticals, active and no longer recruiting.","summary":"Study of Gene Modified Donor T-cells Following TCR Alpha Beta Positive Depleted Stem Cell Transplant is a phase 1/2 interventional study registered as NCT03301168 by Bellicum Pharmaceuticals, with 120 participants enrolled, started 2014-04 and due to reach its primary completion in 2021-05-11. Interventions recorded: BPX-501 T cells and Rimiducid.","status":"active","asOf":"2026-09-16","links":[{"label":"ClinicalTrials.gov NCT03301168","url":"https://clinicaltrials.gov/study/NCT03301168"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["all-leukemia","aml","non-hodgkin-lymphoma","mds"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":["bellicum"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"notes":[],"nct":"NCT03301168","phase":"1/2","setting":"Phase I/II Study of CaspaCIDe® T Cells From an HLA-Partially Matched Family Donor After Negative Selection of TCR αβ+T Cells in Pediatric Patients Affected by Hematological Disorders","sponsor":"Bellicum Pharmaceuticals","enrolled":120,"outcomes":[]},"route":"/trials/nct03301168/","neighbours":{"cancer":[{"id":"all-leukemia","kind":"cancer","name":"Acute lymphoblastic leukaemia","route":"/cancers/all-leukemia/"},{"id":"aml","kind":"cancer","name":"Acute myeloid leukaemia","route":"/cancers/aml/"},{"id":"mds","kind":"cancer","name":"Myelodysplastic syndromes / neoplasms (MDS)","route":"/cancers/mds/"},{"id":"non-hodgkin-lymphoma","kind":"cancer","name":"Non-Hodgkin lymphoma (all types)","route":"/cancers/non-hodgkin-lymphoma/"}],"company":[{"id":"bellicum","kind":"company","name":"Bellicum Pharmaceuticals","route":"/companies/bellicum/"}]}}