{"entity":{"id":"nct03329183","kind":"trial","name":"High-dose FOLFIRI in Advanced Colorectal Cancer Patients With Wild-type UGT1A1*6 and *28","aka":[],"tldr":"A phase 2 trial of UGT1A1 genotyping before irinotecan in Colorectal cancer, run by Shanghai Changzheng Hospital, with a status the registry has not verified recently.","summary":"High-dose FOLFIRI in Advanced Colorectal Cancer Patients With Wild-type UGT1A1*6 and *28 is a phase 2 interventional study registered as NCT03329183 by Shanghai Changzheng Hospital, with 90 participants planned, started 2019-03 and due to reach its primary completion in 2019-03. Interventions recorded: Irinotecan. Conditions recorded: Colorectal Cancer.\n\nLinked to the technology UGT1A1 genotyping before irinotecan because the registry's title names it (\"ugt1a1 6\") and Colorectal cancer among its conditions. Registry record only: no result has been read by an editor.","asOf":"2026-09-22","links":[{"label":"ClinicalTrials.gov NCT03329183","url":"https://clinicaltrials.gov/study/NCT03329183"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["colorectal"],"sections":[],"technologies":["ugt1a1-genotyping"],"targets":[],"drugs":["irinotecan"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT03329183","phase":"2","setting":"High-dose FOLFIRI Versus Standard-dose FOLFIRI or FOLFOX-6 in Advanced Colorectal Cancer Patients With Wild-type UGT1A1*6 and *28: A Randomized, Opened, Phase II Clinical Trial","sponsor":"Shanghai Changzheng Hospital","enrolled":90,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct03329183/","neighbours":{"cancer":[{"id":"colorectal","kind":"cancer","name":"Colorectal cancer","route":"/cancers/colorectal/"}],"technology":[{"id":"ugt1a1-genotyping","kind":"technology","name":"UGT1A1 genotyping before irinotecan","route":"/technologies/ugt1a1-genotyping/"}],"drug":[{"id":"irinotecan","kind":"drug","name":"Irinotecan (and liposomal irinotecan)","route":"/drugs/irinotecan/"}]}}